A reproducible extended ex-vivo normothermic machine liver perfusion protocol utilising improved nutrition and targeted vascular flows

被引：0

作者：

George Clarke ^{[1
]}

Jingwen Mao ^{[2
]}

Angus Hann ^{[3
]}

Yiyu Fan ^{[2
]}

Amita Gupta ^{[3
]}

Anisa Nutu ^{[1
]}

Erwin Buckel Schaffner ^{[2
]}

Kayani Kayani ^{[3
]}

Nicholas Murphy ^{[2
]}

Mansoor N. Bangash ^{[3
]}

Anna L. Casey ^{[4
]}

Isla Wootton ^{[1
]}

Alexander J. Lawson ^{[1
]}

Bobby V. M. Dasari ^{[2
]}

M. Thamara P. R. Perera ^{[3
]}

Hynek Mergental ^{[5
]}

Simon C. Afford ^{[6
]}

机构：

[1] Queen Elizabeth Hospital Birmingham,Liver Unit

[2] University of Birmingham and University Hospitals Birmingham NHS Foundation Trust,Birmingham Biomedical Research Centre, National Institute for Health Research (NIHR)

[3] Institute of Immunology and Immunotherapy,Centre for Liver and Gastrointestinal Research

[4] University of Birmingham,Intensive Care Unit

[5] Ochre-Bio Ltd,Birmingham Acute Care Research Group

[6] Queen Elizabeth Hospital Birmingham,Microbiology Department

[7] Queen Elizabeth Hospital Birmingham,Clinical Biochemistry

[8] Institute of Inflammation and Ageing,undefined

[9] University of Birmingham,undefined

[10] Queen Elizabeth Hospital Birmingham,undefined

[11] Queen Elizabeth Hospital Birmingham,undefined

来源：

Communications Medicine | / 4卷 / 1期

关键词：

D O I：

10.1038/s43856-024-00636-2

中图分类号：

学科分类号：

摘要：

Clarke et al. present a reproducible protocol for the extended normothermic machine perfusion of human livers. Function and are preserved in five human livers perfused between 121–184 h.

引用

共 50 条

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