Observing shear flow induced conformational changes of vWF using TEM

被引：0
|
作者：
Xu, Yangqing [1 ]
Bao, Gang [1 ]
机构：
[1] Biomedical Engineering Soc, Atlanta, United States
来源：
Annals of Biomedical Engineering | 2000年 / 28卷 / SUPPL. 1期
关键词：
Cells - Conformations - Molecules - Proteins - Transmission electron microscopy;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A transmission electron microscopy (TEM) study of vWF conformational change was carried out. TEM images were taken to compare the conformations before and after shear flow was applied. The vWF multimers initially coiled and become extended. The degree of conformational changes increased with the applied shear rate.
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