Subsequent Waves of Convergent Evolution in SARS-CoV-2 Genes and Proteins

被引：1

作者：

Focosi, Daniele ^{[1
]}

Spezia, Pietro Giorgio ^{[2
,3
]}

Maggi, Fabrizio ^{[2
,3
]}

机构：

[1] Pisa Univ Hosp, North Western Tuscany Blood Bank, I-56124 Pisa, Italy

[2] Natl Inst Infect Dis Lazzaro Spallanzani IRCCS, Lab Virol, I-00149 Rome, Italy

[3] Natl Inst Infect Dis Lazzaro Spallanzani IRCCS, Lab Biosecur, I-00149 Rome, Italy

来源：

VACCINES | 2024年 / 12卷 / 08期

关键词：

COVID-19; SARS-CoV-2; evolution; Spike; CORONAVIRUS NUCLEOCAPSID PROTEIN; INFECTIVITY; MUTATIONS; VARIANT;

D O I：

10.3390/vaccines12080887

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Beginning in 2022, following widespread infection and vaccination among the global population, the SARS-CoV-2 virus mainly evolved to evade immunity derived from vaccines and past infections. This review covers the convergent evolution of structural, nonstructural, and accessory proteins in SARS-CoV-2, with a specific look at common mutations found in long-lasting infections that hint at the virus potentially reverting to an enteric sarbecovirus type.

引用

页数：18

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