Subsequent Waves of Convergent Evolution in SARS-CoV-2 Genes and Proteins

被引:1
|
作者
Focosi, Daniele [1 ]
Spezia, Pietro Giorgio [2 ,3 ]
Maggi, Fabrizio [2 ,3 ]
机构
[1] Pisa Univ Hosp, North Western Tuscany Blood Bank, I-56124 Pisa, Italy
[2] Natl Inst Infect Dis Lazzaro Spallanzani IRCCS, Lab Virol, I-00149 Rome, Italy
[3] Natl Inst Infect Dis Lazzaro Spallanzani IRCCS, Lab Biosecur, I-00149 Rome, Italy
关键词
COVID-19; SARS-CoV-2; evolution; Spike; CORONAVIRUS NUCLEOCAPSID PROTEIN; INFECTIVITY; MUTATIONS; VARIANT;
D O I
10.3390/vaccines12080887
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Beginning in 2022, following widespread infection and vaccination among the global population, the SARS-CoV-2 virus mainly evolved to evade immunity derived from vaccines and past infections. This review covers the convergent evolution of structural, nonstructural, and accessory proteins in SARS-CoV-2, with a specific look at common mutations found in long-lasting infections that hint at the virus potentially reverting to an enteric sarbecovirus type.
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页数:18
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