Rational design of a red-light absorbing ruthenium polypyridine complex as a photosensitizer for photodynamic therapy

被引：4

作者：

Fennes, Alessia ^{[1
]}

Montesdeoca, Nicolas ^{[1
]}

Papadopoulos, Zisis ^{[1
]}

Karges, Johannes ^{[1
]}

机构：

[1] Ruhr Univ Bochum, Fac Chem & Biochem, Univ Str 150, D-44780 Bochum, Germany

来源：

CHEMICAL COMMUNICATIONS | 2024年 / 60卷 / 77期

关键词：

Complexation; -; Synthesis; (chemical);

D O I：

10.1039/d4cc04126g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Herein, the computer-guided design, chemical synthesis, and biological evaluation of a Ruc polypyridine complex, that could eradicate cancerous cells upon excitation with red light at 630 nm, is reported. This study details the computer-guided design, synthesis, and biological evaluation of a Ru(ii) polypyridine complex for PDT. The complex can be excited with red light at 630 nm, showing great potential for treating large or deep-seated tumors.

引用

页码：10724 / 10727

页数：4

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