Rational design of a red-light absorbing ruthenium polypyridine complex as a photosensitizer for photodynamic therapy

被引：4
|
作者：
Fennes, Alessia [1 ]
Montesdeoca, Nicolas [1 ]
Papadopoulos, Zisis [1 ]
Karges, Johannes [1 ]
机构：
[1] Ruhr Univ Bochum, Fac Chem & Biochem, Univ Str 150, D-44780 Bochum, Germany
来源：
CHEMICAL COMMUNICATIONS | 2024年 / 60卷 / 77期
关键词：
Complexation; -; Synthesis; (chemical);
D O I：
10.1039/d4cc04126g
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Herein, the computer-guided design, chemical synthesis, and biological evaluation of a Ruc polypyridine complex, that could eradicate cancerous cells upon excitation with red light at 630 nm, is reported. This study details the computer-guided design, synthesis, and biological evaluation of a Ru(ii) polypyridine complex for PDT. The complex can be excited with red light at 630 nm, showing great potential for treating large or deep-seated tumors.
引用
收藏
页码：10724 / 10727
页数：4
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