IDENTIFICATION OF ABNORMAL CHROMOSOMAL COMPLEMENT IN FORMALIN-FIXED, PARAFFIN-EMBEDDED PLACENTAL TISSUE

被引：9
|
作者：
COWLES, TA
ELDER, FFB
TAYLOR, S
机构：
[1] UNIV TEXAS,HLTH SCI CTR,DEPT OBSTET GYNECOL & REPROD SCI,HOUSTON,TX
[2] UNIV TEXAS,HLTH SCI CTR,DEPT PATHOL,HOUSTON,TX
来源：
PRENATAL DIAGNOSIS | 1995年 / 15卷 / 01期
关键词：
FLUORESCENCE IN SITU HYBRIDIZATION (FISH); FORMALIN-FIXED PLACENTA; KARYOTYPE;
D O I：
10.1002/pd.1970150106
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
The objective of this project was to assess the efficacy of fluorescence in situ hybridization (FISH) with chromosome-specific DNA probes to identify chromosome number in formalin-fixed, paraffin-embedded placental specimens. Using this approach, 75 per cent of the karyotypes in 20 formalin-fixed placental samples (comprising aneuploids, triploids, and normals) were correctly identified. As this technology improves, the ability to obtain information regarding chromosomal abnormalities in formalin-fixed, paraffin-embedded placental tissue should improve as well. This technology can potentially provide important cytogenetic information even when fresh tissue is not available for standard karyotypic analysis.
引用
收藏
页码：21 / 26
页数：6
相关论文
共 50 条
  • [1] Preparation of Formalin-fixed Paraffin-embedded Tissue for Immunohistochemistry
    Canene-Adams, Kirstie
    LABORATORY METHODS IN ENZYMOLOGY: CELL, LIPID AND CARBOHYDRATE, 2013, 533 : 225 - 233
  • [2] Molecular identification and subtyping of mycobacterium from formalin-fixed, paraffin-embedded tissue
    Louissaint, A.
    Batten, J. M.
    Kradin, R.
    Iafrate, A. J.
    JOURNAL OF MOLECULAR DIAGNOSTICS, 2007, 9 (05): : 683 - 683
  • [3] Molecular identification of fungi in formalin-fixed and paraffin-embedded skin tissue samples
    Futatsuya, Taketoshi
    Anzawa, Kazushi
    Mochizuki, Takashi
    Hatano, Yutaka
    JOURNAL OF DERMATOLOGY, 2019, 46 (02): : 171 - 172
  • [4] Analysis of Molecular Identification of Bacterial Pathogens on Formalin-Fixed Paraffin-Embedded Tissue
    Hiskey, Matt
    Racsa, Lori
    Guarner, Jeannette
    Moyer, Devlin
    AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 2015, 144 : A224 - A224
  • [5] A RAPID NISSL STAIN FOR FORMALIN-FIXED PARAFFIN-EMBEDDED TISSUE
    PUTT, FA
    JOURNAL OF NEUROSURGERY, 1948, 5 (02) : 211 - 211
  • [6] Protein expression analysis in formalin-fixed, paraffin-embedded tissue
    Steinert, K.
    Becker, K. -F.
    Schott, C.
    Erpenbach, A.
    Porschewski, P.
    MOLECULAR & CELLULAR PROTEOMICS, 2006, 5 (10) : S167 - S167
  • [7] Profiling of lymphoma from formalin-fixed paraffin-embedded tissue
    Robetorye, Ryan S.
    Maguire, Alanna
    Rosenthal, Alison C.
    Rimsza, Lisa M.
    SEMINARS IN HEMATOLOGY, 2019, 56 (01) : 46 - 51
  • [8] PrPSc detection in formalin-fixed paraffin-embedded tissue by ELISA
    Nicholson E.M.
    Greenlee J.J.
    Hamir A.N.
    BMC Research Notes, 4 (1)
  • [9] Massively parallel sequencing of formalin-fixed, paraffin-embedded tissue
    Eyerson, Richard B.
    Glatt-Deeley, Heather R.
    Burian, Linda C.
    Perpetua, Lorrie A.
    Hegde, Upendra P.
    Lambrecht, Richard W.
    Sanders, Mary M.
    CANCER RESEARCH, 2011, 71
  • [10] MammaPrint Molecular Diagnostics on Formalin-Fixed, Paraffin-Embedded Tissue
    Sapino, Anna
    Roepman, Paul
    Linn, Sabine C.
    Snel, Mireille H. J.
    Delahaye, Leonie J. M. J.
    van den Akker, Jeroen
    Glas, Annuska M.
    Simon, Iris M.
    Barth, Neil
    de Snoo, Femke A.
    van 't Veer, Laura J.
    Molinaro, Luca
    Berns, Els M. J. J.
    Wesseling, Jelle
    Riley, Lee B.
    Anderson, David
    Nguyen, Bichlien
    Cox, Charles E.
    JOURNAL OF MOLECULAR DIAGNOSTICS, 2014, 16 (02): : 190 - 197
12345