MAMMARY-TUMOR INHIBITING PROPERTIES OF THE (S,S)-CONFIGURATED [1,2-BIS(4-HYDROXYPHENYL)ETHYLENEDIAMINE]DICHLOROPLATINUM(II) COMPLEX

被引：13
|
作者：
SPRUSS, T [1 ]
GUST, R [1 ]
MULLER, R [1 ]
ENGEL, J [1 ]
SCHONENBERGER, H [1 ]
机构：
[1] ASTA PHARMA AG,W-6000 FRANKFURT 1,GERMANY
来源：
ARCHIV DER PHARMAZIE | 1990年 / 323卷 / 02期
关键词：
D O I：
10.1002/ardp.19903230209
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Mammatumor hemmende Eigenschaften des S,S‐konfigurierten [1,2‐Bis(4‐hydroxyphenyl)ethylendiamin] dichloroplatin(II)‐Complexes [(S,S)‐1,2‐Bis(4‐hydroxyphenyl)ethylendiamin]dichloroplatin)platin(II) zeigt einen starken, Dosis‐abhängigen Effekt am hormonabhängigen MXT‐Mammacarcinom der Maus. Die R,R/S,S‐konfigurierte Verbindung ist deutlich schwächer wirksam.
引用
收藏
页码：99 / 102
页数：4
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