MAMMARY-TUMOR INHIBITING PROPERTIES OF THE (S,S)-CONFIGURATED [1,2-BIS(4-HYDROXYPHENYL)ETHYLENEDIAMINE]DICHLOROPLATINUM(II) COMPLEX

被引：13

作者：

SPRUSS, T ^{[1
]}

GUST, R ^{[1
]}

MULLER, R ^{[1
]}

ENGEL, J ^{[1
]}

SCHONENBERGER, H ^{[1
]}

机构：

[1] ASTA PHARMA AG,W-6000 FRANKFURT 1,GERMANY

来源：

ARCHIV DER PHARMAZIE | 1990年 / 323卷 / 02期

关键词：

D O I：

10.1002/ardp.19903230209

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Mammatumor hemmende Eigenschaften des S,S‐konfigurierten [1,2‐Bis(4‐hydroxyphenyl)ethylendiamin] dichloroplatin(II)‐Complexes [(S,S)‐1,2‐Bis(4‐hydroxyphenyl)ethylendiamin]dichloroplatin)platin(II) zeigt einen starken, Dosis‐abhängigen Effekt am hormonabhängigen MXT‐Mammacarcinom der Maus. Die R,R/S,S‐konfigurierte Verbindung ist deutlich schwächer wirksam.

引用

页码：99 / 102

页数：4

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