SYNTHESIS OF ENANTIOMERICALLY PURE BETA-AMINO AND GAMMA-AMINO-ACIDS FROM ASPARTIC AND GLUTAMIC-ACID DERIVATIVES

被引：0

作者：

ELMARINI, A

ROUMESTANT, ML

VIALLEFONT, P

RAZAFINDRAMBOA, D

BONATO, M

FOLLET, M

机构：

[1] UNIV MONTPELLIER SCI & TECH LANGUEDOC 2,URA 468,PL E BATAILLON,F-34095 MONTPELLIER 5,FRANCE

[2] SOC EXPANSIA,F-30390 ARAMON,FRANCE

来源：

SYNTHESIS-STUTTGART | 1992年 / 11期

关键词：

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient synthesis of enantiomerically pure beta- and gamma-amino acids starting from commercially available aspartic and glutamic acid derivatives is described. The acid function, alpha to the amino group, is first transformed to a good leaving group and the product reacted with organocuprates to yield beta- and gamma-amino esters. After deprotection beta- and gamma-amino acids are obtained in good overall yields.

引用

页码：1104 / 1108

页数：5

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