ASYMMETRIC-SYNTHESIS OF THE AB-RING OF AKLAVINONE

被引：10
|
作者：
DAVIS, FA
KUMAR, A
机构：
[1] Department of Chemistry, Drexel University, Philadelphia
来源：
TETRAHEDRON LETTERS | 1991年 / 32卷 / 52期
基金：
美国国家卫生研究院;
关键词：
D O I：
10.1016/0040-4039(91)80561-J
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A formal synthesis of the AB-ring of aklavinone 3 was achieved via the asymmetric synthesis of diol 8 prepared in three steps from tetralone 5. The crucial step involved the asymmetric hydroxylation of 5 in greater-than-or-equal-to 95% ee using (camphorylsulfonyl)oxaziridine derivative (+)-4b.
引用
收藏
页码：7671 / 7674
页数：4
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