ASYMMETRIC-SYNTHESIS OF CHIRAL FLUORINATED COMPOUNDS

被引：17
|
作者：
ISEKI, K
KOBAYASHI, Y
机构：
[1] MEC Laboratory, Daikin Industries Ltd.
来源：
JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN | 1994年 / 52卷 / 01期
关键词：
CHIRAL FLUORINATED COMPOUNDS; ASYMMETRIC SYNTHESIS; MONOFLUORINATION; FLUOROALKYLATION; TRIFLUOROMETHYLATION;
D O I：
10.5059/yukigoseikyokaishi.52.40
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The synthesis of chiral compounds having fluorine atoms has become an important part of organofluorine chemistry in connection with analytical, biological and medicinal chemistry and opto-electric substances such as liquid crystals. This review is focused on asymmetric synthesis of chiral compounds having a fluorine atom or a fluoroalkyl group (especially a trifluoromethyl group). The examples cited in this review are divided in three different types; (a) asymmetric monofluorination, (b) asymmetric fluoroalkylation (trifluoromethylation), and (c) conversion from prochiral fluorinated compounds.
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页码：40 / 48
页数：9
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