ASYMMETRIC-SYNTHESIS OF CHIRAL FLUORINATED COMPOUNDS

被引：17
|
作者：
ISEKI, K
KOBAYASHI, Y
机构：
[1] MEC Laboratory, Daikin Industries Ltd.
来源：
JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN | 1994年 / 52卷 / 01期
关键词：
CHIRAL FLUORINATED COMPOUNDS; ASYMMETRIC SYNTHESIS; MONOFLUORINATION; FLUOROALKYLATION; TRIFLUOROMETHYLATION;
D O I：
10.5059/yukigoseikyokaishi.52.40
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The synthesis of chiral compounds having fluorine atoms has become an important part of organofluorine chemistry in connection with analytical, biological and medicinal chemistry and opto-electric substances such as liquid crystals. This review is focused on asymmetric synthesis of chiral compounds having a fluorine atom or a fluoroalkyl group (especially a trifluoromethyl group). The examples cited in this review are divided in three different types; (a) asymmetric monofluorination, (b) asymmetric fluoroalkylation (trifluoromethylation), and (c) conversion from prochiral fluorinated compounds.
引用
收藏
页码：40 / 48
页数：9
相关论文
共 50 条
  • [31] CAMPHOR DERIVATIVES AS CHIRAL AUXILIARIES IN ASYMMETRIC-SYNTHESIS
    OPPOLZER, W
    TETRAHEDRON, 1987, 43 (09) : 1969 - 2004
  • [32] CHIRAL ALCOHOLATES IN ASYMMETRIC-SYNTHESIS - A RENEWAL IN THE SEARCH FOR CHIRAL BASES
    VADECARD, J
    PLAQUEVENT, JC
    DUHAMEL, L
    DUHAMEL, P
    TOUPET, L
    JOURNAL OF ORGANIC CHEMISTRY, 1994, 59 (09): : 2285 - 2286
  • [33] ASYMMETRIC-SYNTHESIS OF CHIRAL PHOSPHORUS-COMPOUNDS BY DESTRUCTIVE-SELECTIVE OXIDATION OF P(III) COMPOUNDS BY MEANS OF CHIRAL OXAZIRIDINES
    VERFURTH, U
    UGI, I
    CHEMISCHE BERICHTE, 1991, 124 (07) : 1627 - 1634
  • [34] ASYMMETRIC-SYNTHESIS OF CHIRAL SULFINATE ESTERS AND SULFOXIDES - SYNTHESIS OF SULFORAPHANE
    WHITESELL, JK
    WONG, MS
    JOURNAL OF ORGANIC CHEMISTRY, 1994, 59 (03): : 597 - 601
  • [35] ASYMMETRIC-SYNTHESIS WITH CHIRAL HYDROGENOLYSABLE AMINES - A SHORT SYNTHESIS OF (-)-ISORETRONECANOL
    HAVIARI, G
    CELERIER, JP
    PETIT, H
    LHOMMET, G
    TETRAHEDRON LETTERS, 1993, 34 (10) : 1599 - 1600
  • [36] CONSTRUCTION OF A KEY INTERMEDIATE IN THE ASYMMETRIC-SYNTHESIS OF CHIRAL TAXANES
    BOA, AN
    CLARK, J
    JENKINS, PR
    LAWRENCE, NJ
    JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1993, (02) : 151 - 152
  • [37] CHIRAL RESOLUTIONS, ASYMMETRIC-SYNTHESIS AND AMPLIFICATION OF ENANTIOMERIC EXCESS
    DEMIN, M
    LEVY, G
    MICHEAU, JC
    JOURNAL DE CHIMIE PHYSIQUE ET DE PHYSICO-CHIMIE BIOLOGIQUE, 1988, 85 (05) : 603 - 619
  • [38] ALPHA-CHIRAL ALLYLBORONATES - REAGENTS FOR ASYMMETRIC-SYNTHESIS
    HOFFMANN, RW
    PURE AND APPLIED CHEMISTRY, 1988, 60 (01) : 123 - 130
  • [39] CHIRAL LEAVING GROUP - ASYMMETRIC-SYNTHESIS OF LIMONENE AND BISABOLENE
    SAKANE, S
    FUJIWARA, J
    MARUOKA, K
    YAMAMOTO, H
    TETRAHEDRON, 1986, 42 (08) : 2193 - 2201
  • [40] ASYMMETRIC-SYNTHESIS OF SULFINIMINES - CHIRAL AMMONIA IMINE SYNTHONS
    DAVIS, FA
    REDDY, RE
    REDDY, RT
    PORTONOVO, PM
    SZEWCZYK, JM
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1993, 205 : 19 - ORGN
12345