TREATMENT OF DIARRHEA IN CARCINOID-SYNDROME WITH ONDANSETRON, TROPISETRON, AND CLONIDINE

被引：0

作者：

SCHWORER, H ^{[1
]}

MUNKE, H ^{[1
]}

STOCKMANN, F ^{[1
]}

RAMADORI, G ^{[1
]}

机构：

[1] UNIV GOTTINGEN,DEPT MED,DIV GASTROENTEROL & ENDOCRINOL,W-3400 GOTTINGEN,GERMANY

来源：

AMERICAN JOURNAL OF GASTROENTEROLOGY | 1995年 / 90卷 / 04期

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D O I：

暂无

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

A 69-yr-old man with known carcinoid syndrome treated with octreotide and interferon-alpha(2b) developed diarrhea, with six to eight watery to semiliquid stools per day. Diminished stool frequency and increased stool consistency were obtained by treatment with the 5-hydroxytryptamine-3 receptor antagonists ondansetron and tropisetron, Successful alleviation of the diarrhea was also observed with the alpha 2-receptor agonist clonidine, These observations indicate that these classes of drugs should be evaluated in a controlled trial in patients with carcinoid-associated diarrhea.

引用

页码：645 / 648

页数：4

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