REGIONAL MAPPING OF LOCI FROM HUMAN-CHROMOSOME 2Q TO SHEEP CHROMOSOME 2Q

被引：17
|
作者：
ANSARI, HA
PEARCE, PD
MAHER, DW
MALCOLM, AA
WOOD, NJ
PHUA, SH
BROAD, TE
机构：
[1] AgResearch Grasslands Research Centre, Palmerston North
来源：
GENOMICS | 1994年 / 20卷 / 01期
关键词：
D O I：
10.1006/geno.1994.1137
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
The human chromosome 2q loci, fibronectin 1 (FN1), the alpha 1 chain of type III collagen (COL3A1), and the delta subunit of the muscle acetylcholine receptor (CHRND) have been regionally assigned to sheep chromosome 2q by in situ hybridization. COL3A1 is pericentromeric (2q12-q21), while FN1 and CHRND are in the subterminal region at 2q41-q44 and 2q42-qter, respectively. The mapping of FN1 assigns the sheep syntenic group U11, which contains FN1, villin 1 (VIL1), isocitrate dehydrogenase 1 (IDH1), and gamma subunit of the muscle acetylcholine receptor (CHRNG), to sheep chromosome 2q. Inhibin-alpha (INHA) is also assigned to sheep chromosome 2q as FN1 and INHA compose sheep linkage group 3. These seven loci are members of a conserved chromosomal segment in human, mouse, and sheep. (C) 1994 Academic Press, Inc.
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页码：122 / 124
页数：3
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