AN ION-STORAGE TIME-OF-FLIGHT MASS-SPECTROMETER FOR ANALYSIS OF ELECTROSPRAY IONS

被引：32
|
作者：
BOYLE, JG [1 ]
WHITEHOUSE, CM [1 ]
FENN, JB [1 ]
机构：
[1] YALE UNIV,DEPT CHEM ENGN,NEW HAVEN,CT 06520
来源：
RAPID COMMUNICATIONS IN MASS SPECTROMETRY | 1991年 / 5卷 / 09期
关键词：
D O I：
10.1002/rcm.1290050906
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
A preliminary design and implementation of a novel approach to electrospray-mass spectrometry are described. Based on a time-of-flight mass analysis, the instrument provides several important advantages for on-line mass analysis: 1, simplicity, ease of use and low manufacturing cost; 2, rapid scan speed, yielding quasi-instantaneous full mass scans at repetition rates up to several kHz; 3, soft ionization and accurate mass determination of extremely large analyte molecules; 4, high sensitivity.
引用
收藏
页码：400 / 405
页数：6
相关论文
共 50 条
  • [21] A TIME-OF-FLIGHT MASS-SPECTROMETER FOR MEASUREMENT OF SECONDARY ION MASS-SPECTRA
    CHAIT, BT
    STANDING, KG
    INTERNATIONAL JOURNAL OF MASS SPECTROMETRY AND ION PROCESSES, 1981, 40 (02): : 185 - 193
  • [22] CONSTRUCTION OF A SHUTTERED TIME-OF-FLIGHT MASS-SPECTROMETER FOR SELECTIVE ION DETECTION
    RINNEN, KD
    KLINER, DAV
    BLAKE, RS
    ZARE, RN
    REVIEW OF SCIENTIFIC INSTRUMENTS, 1989, 60 (04): : 717 - 719
  • [23] CLUSTER ION SPECTROSCOPY AND PHOTOCHEMISTRY IN A REFLECTRON TIME-OF-FLIGHT MASS-SPECTROMETER
    DUNCAN, MA
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1990, 200 : 124 - ANYL
  • [24] ION OPTICS OF A TIME-OF-FLIGHT MASS-SPECTROMETER WITH ELECTROSTATIC SECTOR ANALYZERS
    SAKURAI, T
    ITO, H
    MATSUO, T
    NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 1995, 363 (1-2): : 426 - 428
  • [25] TIME-OF-FLIGHT MASS-SPECTROMETER FOR IMPULSE FACILITIES
    SKINNER, KA
    STALKER, RJ
    AIAA JOURNAL, 1994, 32 (11) : 2325 - 2328
  • [26] DEVELOPMENT OF TIME-OF-FLIGHT MASS-SPECTROMETER SYSTEMS
    WOLLNIK, H
    ANALYTICAL INSTRUMENTATION, 1987, 16 (01): : 15 - 29
  • [27] Electrospray ionization time-of-flight mass spectrometer for elemental analysis
    Mahoney, PP
    Guzowski, JP
    Ray, SJ
    Hieftje, GM
    APPLIED SPECTROSCOPY, 1997, 51 (10) : 1464 - 1470
  • [28] RESOLUTION IN THE LINEAR TIME-OF-FLIGHT MASS-SPECTROMETER
    OPSAL, RB
    OWENS, KG
    REILLY, JP
    ANALYTICAL CHEMISTRY, 1985, 57 (09) : 1884 - 1889
  • [29] LASER SPECTROSCOPY OF MASS-SELECTED IONS IN A REFLECTRON TIME-OF-FLIGHT MASS-SPECTROMETER
    WILLEY, KF
    ROBBINS, DL
    YEH, CS
    DUNCAN, MA
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1991, 201 : 228 - PHYS
  • [30] A time-of-flight detector of low-energy ions for an accelerating mass-spectrometer
    Alinovskii, N. I.
    Konstantinov, E. S.
    Parkhomchuk, V. V.
    Petrozhitskii, A. V.
    Rastigeev, S. A.
    Reva, V. B.
    INSTRUMENTS AND EXPERIMENTAL TECHNIQUES, 2009, 52 (02) : 234 - 237
12345