SYNTHESIS AND PHARMACOLOGICAL STUDY OF A THIOPHENE ANALOG OF MOPROLOL AND RELATED-COMPOUNDS

被引：4
|
作者：
ELASHMAWY, MB [1 ]
LISSAVETZKY, J [1 ]
DARIAS, V [1 ]
MARTINHERRERA, D [1 ]
机构：
[1] UNIV LA LAGUNA,FAC FARM,DEPT FARMACAGNOSIA FARMACODINAMIA,LA LAGUNA,SPAIN
来源：
ARCHIV DER PHARMAZIE | 1991年 / 324卷 / 01期
关键词：
D O I：
10.1002/ardp.19913240112
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The syntheses of the thiophenic analogue of Moprolol (1d) and of its related compound 1a are described. From a preliminary pharmacological evaluation compound 1d seems worthy of further studies due to its notable beta-blocking activity and its remarkable anti-platelet aggregation action.
引用
收藏
页码：45 / 48
页数：4
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