SYNTHESIS AND PHARMACOLOGICAL STUDY OF A THIOPHENE ANALOG OF MOPROLOL AND RELATED-COMPOUNDS

被引：4

作者：

ELASHMAWY, MB ^{[1
]}

LISSAVETZKY, J ^{[1
]}

DARIAS, V ^{[1
]}

MARTINHERRERA, D ^{[1
]}

机构：

[1] UNIV LA LAGUNA,FAC FARM,DEPT FARMACAGNOSIA FARMACODINAMIA,LA LAGUNA,SPAIN

来源：

ARCHIV DER PHARMAZIE | 1991年 / 324卷 / 01期

关键词：

D O I：

10.1002/ardp.19913240112

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The syntheses of the thiophenic analogue of Moprolol (1d) and of its related compound 1a are described. From a preliminary pharmacological evaluation compound 1d seems worthy of further studies due to its notable beta-blocking activity and its remarkable anti-platelet aggregation action.

引用

页码：45 / 48

页数：4

共 50 条

[21] SYNTHESIS OF EXOGONIC ACID AND RELATED-COMPOUNDS
NISHIYAMA, T
WOODHALL, JF
LAWSON, EN
KITCHING, W
JOURNAL OF ORGANIC CHEMISTRY, 1989, 54 (09): : 2183 - 2189
[22] SYNTHESIS OF GUAIPYRIDINE, EPIGUAIPYRIDINE, AND RELATED-COMPOUNDS
KOYAMA, J
OKATANI, T
TAGAHARA, K
SUZUTA, Y
IRIE, H
HETEROCYCLES, 1987, 26 (04) : 925 - 927
[23] SYNTHESIS OF SHIKALKIN AND CERTAIN RELATED-COMPOUNDS
NOVIKOV, VL
BALANEVA, NN
MOISEENKOV, AM
ELYAKOV, GB
BULLETIN OF THE RUSSIAN ACADEMY OF SCIENCES-DIVISION OF CHEMICAL SCIENCE, 1992, 41 (08): : 1485 - 1494
[24] FACILE SYNTHESIS OF ZYMOSTEROL AND RELATED-COMPOUNDS
OGIHARA, N
MORISAKI, M
CHEMICAL & PHARMACEUTICAL BULLETIN, 1988, 36 (07) : 2724 - 2725
[25] A SIMPLE SYNTHESIS OF TROPONES AND RELATED-COMPOUNDS
BARBIER, M
BARTON, DHR
DEVYS, M
TOPGI, RS
TETRAHEDRON, 1987, 43 (21) : 5031 - 5038
[26] SYNTHESIS OF ANTIFUNGAL PYRAZOLONES AND RELATED-COMPOUNDS
SUMAN, SP
BAHEL, SC
JOURNAL OF THE INDIAN CHEMICAL SOCIETY, 1980, 57 (02) : 212 - 215
[27] ENANTIOSELECTIVE SYNTHESIS OF (-)-LYCOSERONE AND RELATED-COMPOUNDS
KUHNKE, J
BOHLMANN, F
LIEBIGS ANNALEN DER CHEMIE, 1988, (08): : 743 - 748
[28] EXPEDIENT SYNTHESIS OF EBSELEN AND RELATED-COMPOUNDS
ENGMAN, L
HALLBERG, A
JOURNAL OF ORGANIC CHEMISTRY, 1989, 54 (12): : 2964 - 2966
[29] A NOVEL SYNTHESIS OF BRASSINOLIDE AND RELATED-COMPOUNDS
SHAN, ZW
JIANG, B
PAN, XF
JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1989, (10) : 612 - 614
[30] FACILE SYNTHESIS OF TETRAZOLYLCHROMONOIDS AND RELATED-COMPOUNDS
PATONAY, T
LEVAI, A
ARCHIV DER PHARMAZIE, 1994, 327 (03) : 181 - 186

← 1 2 3 4 5 →