A NEW SYNTHESIS OF 2-SUBSTITUTED DL-TRYPTOPHAN DERIVATIVES

被引：0
|
作者：
BALSAMINI, C [1 ]
DIAMANTINI, G [1 ]
DURANTI, A [1 ]
SPADONI, G [1 ]
TONTINI, A [1 ]
机构：
[1] UNIV URBINO,IST CHIM FARMACEUT & TOSSICOL,I-61029 URBINO,ITALY
来源：
SYNTHESIS-STUTTGART | 1995年 / 04期
关键词：
DEHYDROAMINO ACIDS; INDOLES; MICHAEL-TYPE ADDITION; 2-SUBSTITUTED TRYPTOPHANS; 2-BROMOTRYPTOPHAN SYNTHESIS;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Methyl 2-substituted N-(diphenylmethylene)-DL-tryptophanates were prepared by means of Lewis acid catalysed Michael-type addition of methyl N-(diphenylmethylene)dehydroalaninate to suitable 2-substituted indoles. Hydrolysis of these tryptophan derivatives affords the corresponding amino acids. Examples of selective deprotection of either the amino or carboxylic group are reported.
引用
收藏
页码：370 / 372
页数：3
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