A NEW SYNTHESIS OF 2-SUBSTITUTED DL-TRYPTOPHAN DERIVATIVES

被引：0

作者：

BALSAMINI, C ^{[1
]}

DIAMANTINI, G ^{[1
]}

DURANTI, A ^{[1
]}

SPADONI, G ^{[1
]}

TONTINI, A ^{[1
]}

机构：

[1] UNIV URBINO,IST CHIM FARMACEUT & TOSSICOL,I-61029 URBINO,ITALY

来源：

SYNTHESIS-STUTTGART | 1995年 / 04期

关键词：

DEHYDROAMINO ACIDS; INDOLES; MICHAEL-TYPE ADDITION; 2-SUBSTITUTED TRYPTOPHANS; 2-BROMOTRYPTOPHAN SYNTHESIS;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Methyl 2-substituted N-(diphenylmethylene)-DL-tryptophanates were prepared by means of Lewis acid catalysed Michael-type addition of methyl N-(diphenylmethylene)dehydroalaninate to suitable 2-substituted indoles. Hydrolysis of these tryptophan derivatives affords the corresponding amino acids. Examples of selective deprotection of either the amino or carboxylic group are reported.

引用

页码：370 / 372

页数：3

共 50 条

[21] Synthesis and Antimicrobial Activity of Some New 2-Substituted Benzothiazole Derivatives
Rajeeva, B.
Srinivasulu, N.
Shantakumar, S. M.
E-JOURNAL OF CHEMISTRY, 2009, 6 (03) : 775 - 779
[22] POLAROGRAPHY OF EUROPIUM(III)-DL-TRYPTOPHAN COMPLEX
LAL, S
BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 1973, 46 (07) : 2232 - 2232
[23] Synthesis of Novel 2-Substituted Thiadiazole Derivatives
Xue, Shouqing
Ma, Yuanzhong
Li, Weinan
JOURNAL OF THE CHEMICAL SOCIETY OF PAKISTAN, 2018, 40 (02): : 383 - 387
[24] Synthesis and characterization of new 2-substituted isoindoline derivatives of α-amino acids
Mancilla, T
Carrillo, L
Zamudio-Rivera, LS
Beltrán, HI
Farfán, N
ORGANIC PREPARATIONS AND PROCEDURES INTERNATIONAL, 2001, 33 (04) : 341 - 349
[25] Progress in the Synthesis of 2-Substituted Benzoxazoles Derivatives
Xiao, Liwei
Gao, Hongjie
Kong, Jie
Liu, Guangxian
Peng, Xiaoxia
Wang, Shujun
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2014, 34 (06) : 1048 - 1060
[26] NOTE ON THE RESOLUTION OF DL-TRYPTOPHAN BY PAPER CHROMATOGRAPHY
CLOSS, K
HAUG, CM
CHEMISTRY & INDUSTRY, 1953, (05) : 103 - 103
[27] CRYSTAL-STRUCTURE OF DL-TRYPTOPHAN FORMATE
BYE, E
MOSTAD, A
ROMMING, C
ACTA CHEMICA SCANDINAVICA, 1973, 27 (02): : 471 - 484
[28] SYNTHESIS OF 2-SUBSTITUTED AND 5-SUBSTITUTED THIOPHENE DERIVATIVES
GARRIGUES, B
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, 1990, 53 (1-4): : 75 - 79
[29] PAPAIN RESOLUTION OF DL-TRYPTOPHAN - OPTICAL SPECIFICITY OF CARBOXYPEPTIDASE
HANSON, HT
SMITH, EL
JOURNAL OF BIOLOGICAL CHEMISTRY, 1949, 179 (02) : 815 - 818
[30] NEW SYNTHESIS OF 2-SUBSTITUTED RESORCINOLS
SCHAMP, N
VERHE, R
DEBUYCK, L
TETRAHEDRON, 1973, 29 (23) : 3857 - 3859

← 1 2 3 4 5 →