Development of Sarcoidosis Following Completion of Treatment for Hepatitis C with Pegylated Interferon-alpha 2a and Ribavirin: A Case Report and Literature Review

被引：17

作者：

Gayet, Alberic-Rembrandt ^{[1
]}

Plaisance, Patrick ^{[1
]}

Bergmann, Jean-Francois ^{[2
]}

Mouly, Stephane ^{[2
]}

机构：

[1] Lariboisiere Hosp, AP HP, Emergency Dept, Paris, France

[2] Lariboisiere Hosp, AP HP, Dept Internal Med, Paris, France

来源：

CLINICAL MEDICINE & RESEARCH | 2010年 / 8卷 / 3-4期

关键词：

Chronic hepatitis C; Interferon-alpha and ribavirin combination therapy; Sarcoidosis; Spontaneous recovery;

D O I：

10.3121/cmr.2010.886

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Sarcoidosis is a chronic inflammatory multisystem disease of unknown etiology. We report on a woman, aged 57 years, presenting with typical sarcoidosis occurring two months after completion of a six-month course of interferon-a and ribavirin for chronic hepatitis C virus infection. The current observation is interesting with regard to the time elapsed between the occurrence of symptoms and antiviral treatment withdrawal, and spontaneous recovery after ten months of follow-up. Pathophysiological mechanisms involved in the development of antiviral therapyinduced sarcoidosis are discussed.

引用

页码：163 / 167

页数：5

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