Development of Sarcoidosis Following Completion of Treatment for Hepatitis C with Pegylated Interferon-alpha 2a and Ribavirin: A Case Report and Literature Review

被引：17
|
作者：
Gayet, Alberic-Rembrandt [1 ]
Plaisance, Patrick [1 ]
Bergmann, Jean-Francois [2 ]
Mouly, Stephane [2 ]
机构：
[1] Lariboisiere Hosp, AP HP, Emergency Dept, Paris, France
[2] Lariboisiere Hosp, AP HP, Dept Internal Med, Paris, France
来源：
CLINICAL MEDICINE & RESEARCH | 2010年 / 8卷 / 3-4期
关键词：
Chronic hepatitis C; Interferon-alpha and ribavirin combination therapy; Sarcoidosis; Spontaneous recovery;
D O I：
10.3121/cmr.2010.886
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Sarcoidosis is a chronic inflammatory multisystem disease of unknown etiology. We report on a woman, aged 57 years, presenting with typical sarcoidosis occurring two months after completion of a six-month course of interferon-a and ribavirin for chronic hepatitis C virus infection. The current observation is interesting with regard to the time elapsed between the occurrence of symptoms and antiviral treatment withdrawal, and spontaneous recovery after ten months of follow-up. Pathophysiological mechanisms involved in the development of antiviral therapyinduced sarcoidosis are discussed.
引用
收藏
页码：163 / 167
页数：5
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