NONSTEREOSPECIFIC FORMATION OF 3-ALPHA,7-ALPHA,24-TRIHYDROXY-5-BETA-CHOLESTAN-26-OIC ACID DURING CHENODEOXYCHOLIC ACID BIOSYNTHESIS

被引：0
|
作者：
KOBAYASHI, N
HAGIWARA, C
MORISAKI, M
YURI, M
FUJIMOTO, Y
机构：
[1] KYORITSU COLL PHARMACEUT SCI, MINATO KU, TOKYO 105, JAPAN
[2] TOKYO INST TECHNOL, DEPT CHEM, MEGURO KU, TOKYO 152, JAPAN
来源：
CHEMICAL & PHARMACEUTICAL BULLETIN | 1994年 / 42卷 / 07期
关键词：
CHENODEOXYCHOLIC ACID; BETA-OXIDATION; BILE ACID; 3-ALPHA; 7-ALPHA-DIHYDROXY-5-BETA-CHOLESTAN-26-OIC ACID; 7-ALPHA; 24-TRIHYDROXY-5-BETA-CHOLESTAN-26-OIC ACID;
D O I：
暂无
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Incubation of 3 alpha, 7 alpha-dihydroxy-5 beta-cholestan-26-oic acid and its Delta(24)-analog with rat liver homogenate produced a mixture of C-24,25 diastereoisomers of 3<alpha),7 alpha,24-trihydroxy-5 beta-cholestan-26-oic acid, a key intermediate of chenodeoxycholic acid biosynthesis.
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页码：1536 / 1538
页数：3
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