NONSTEREOSPECIFIC FORMATION OF 3-ALPHA,7-ALPHA,24-TRIHYDROXY-5-BETA-CHOLESTAN-26-OIC ACID DURING CHENODEOXYCHOLIC ACID BIOSYNTHESIS

被引：0

作者：

KOBAYASHI, N

HAGIWARA, C

MORISAKI, M

YURI, M

FUJIMOTO, Y

机构：

[1] KYORITSU COLL PHARMACEUT SCI, MINATO KU, TOKYO 105, JAPAN

[2] TOKYO INST TECHNOL, DEPT CHEM, MEGURO KU, TOKYO 152, JAPAN

来源：

CHEMICAL & PHARMACEUTICAL BULLETIN | 1994年 / 42卷 / 07期

关键词：

CHENODEOXYCHOLIC ACID; BETA-OXIDATION; BILE ACID; 3-ALPHA; 7-ALPHA-DIHYDROXY-5-BETA-CHOLESTAN-26-OIC ACID; 7-ALPHA; 24-TRIHYDROXY-5-BETA-CHOLESTAN-26-OIC ACID;

D O I：

暂无

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Incubation of 3 alpha, 7 alpha-dihydroxy-5 beta-cholestan-26-oic acid and its Delta(24)-analog with rat liver homogenate produced a mixture of C-24,25 diastereoisomers of 3<alpha),7 alpha,24-trihydroxy-5 beta-cholestan-26-oic acid, a key intermediate of chenodeoxycholic acid biosynthesis.

引用

页码：1536 / 1538

页数：3

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