SYNTHESIS AND APPLICATION OF IMIDAZOLE DERIVATIVES - SYNTHESIS OF PYRIDO[1,2-A]BENZIMIDAZOLONE DERIVATIVES

被引：14
|
作者：
OHTA, S
YUASA, T
NARITA, Y
KAWASAKI, I
MINAMII, E
YAMASHITA, M
机构：
来源：
HETEROCYCLES | 1991年 / 32卷 / 10期
关键词：
D O I：
10.3987/COM-91-5805
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Pyrido[1,2-a]benzimidazole derivatives (12a and 19a) were synthesized in moderate yields via an intramolecular aldol-condensation of 2-acetyl-1-formylmethylbenzimidazole (11) and an intramolecular acylation of the acylimidzolide (18) prepared from 2-ethoxycarbonylmethyl-1-(2-carboxyethyl)-benzimidazole (17), respectively.
引用
收藏
页码：1923 / 1931
页数：9
相关论文
共 50 条
  • [41] Microwave-assisted synthesis of pyrido[1,2-a]benzimidazole derivatives of β-aryloxyquinoline and their antimicrobial and antituberculosis activities
    Chetan B. Sangani
    Hardik H. Jardosh
    Manish P. Patel
    Ranjan G. Patel
    Medicinal Chemistry Research, 2013, 22 : 3035 - 3047
  • [42] Microwave-assisted synthesis of pyrido[1,2-a]benzimidazole derivatives of β-aryloxyquinoline and their antimicrobial and antituberculosis activities
    Sangani, Chetan B.
    Jardosh, Hardik H.
    Patel, Manish P.
    Patel, Ranjan G.
    MEDICINAL CHEMISTRY RESEARCH, 2013, 22 (06) : 3035 - 3047
  • [43] STUDIES IN IMIDAZOLE SERIES .64. SYNTHESIS OF IMIDAZO[1,2-A]IMIDAZOLE DERIVATIVES ON BASE OF 2-HALOGENIMIDAZOLES
    PRIIMENKO, BA
    KOCHERGI.PM
    KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 1971, (09): : 1243 - +
  • [44] DERIVATIVES OF IMIDAZOLE .3. SYNTHESIS AND PHARMACOLOGICAL ACTIVITIES OF NITRILES AMIDES AND CARBOXYLIC ACID DERIVATIVES OF IMIDAZO(1,2-A)PYRIDINE
    ALMIRANTE, L
    MUGNAINI, A
    RUGARLI, P
    GAMBA, A
    ZEFELIPPO, E
    DETOMA, N
    MURMANN, W
    JOURNAL OF MEDICINAL CHEMISTRY, 1969, 12 (01) : 122 - +
  • [45] Synthesis and reactivity of novel pyrrolo[1,2-a]pyrazine derivatives
    Maxim Voievudskyi
    Valeriia Astakhina
    Oxana Kryshchyk
    Olena Petuhova
    Svetlana Shyshkina
    Monatshefte für Chemie - Chemical Monthly, 2016, 147 : 783 - 789
  • [46] Two alternatives for the synthesis of pyrrolo[1,2-a] quinoxaline derivatives
    Harrak, Y.
    Weber, S.
    Gomez, A. B.
    Rosell, G.
    Pujol, M. D.
    ARKIVOC, 2007, : 251 - 259
  • [47] Synthesis of imidazo[1,2-a] pyridine derivatives as antiviral agents
    Mavel, S
    Renou, JL
    Galtier, C
    Snoeck, R
    Andrei, G
    Balzarini, J
    De Clercq, E
    Gueiffier, A
    ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH, 2001, 51 (04): : 304 - 309
  • [48] Synthesis and reactivity of novel pyrrolo[1,2-a]pyrazine derivatives
    Voievudskyi, Maxim
    Astakhina, Valeriia
    Kryshchyk, Oxana
    Petuhova, Olena
    Shyshkina, Svetlana
    MONATSHEFTE FUR CHEMIE, 2016, 147 (04): : 783 - 789
  • [49] SYNTHESIS AND ANTISEROTONIN ACTIVITY OF PYRROLO[1,2-A]-IMIDAZOL DERIVATIVES
    KOCHERGIN, PM
    MASHKOVSKII, MD
    DRUZHININA, AA
    KAMINKA, ME
    KHIMIKO-FARMATSEVTICHESKII ZHURNAL, 1976, 10 (04): : 59 - 62
  • [50] A new approach to the synthesis of pyrrolo[1,2-a]indole derivatives
    Ryabova, S. Yu.
    Alekseeva, L. M.
    Lisitsa, E. A.
    Masterova, N. S.
    Kiselev, S. S.
    Evstratova, M. I.
    Granik, V. G.
    RUSSIAN CHEMICAL BULLETIN, 2006, 55 (12) : 2271 - 2277
12345