ANTIOXIDANT EFFECT OF CALMODULIN ANTAGONISTS IN RAT-BRAIN HOMOGENATE

被引：0
|
作者：
HARA, S
ENDO, T
KURIIWA, F
KANO, S
IWATA, N
机构：
来源：
RESEARCH COMMUNICATIONS IN CHEMICAL PATHOLOGY AND PHARMACOLOGY | 1992年 / 76卷 / 03期
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中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
Several calmodulin antagonists, W-7, amitriptyline, trifluoperazine, chlorpromazine, dibucaine, prenylamine, calmidazolium, and compound 48/80, inhibited lipid peroxidation induced non-enzymatically in rat brain homogenate by ascorbate and Fe2+. Suggestions of involvement of calmodulin in various oxidative cellular responses, based on experiments using calmodulin antagonists, may need to be re-evaluated.
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页码：367 / 370
页数：4
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