ANTIOXIDANT EFFECT OF CALMODULIN ANTAGONISTS IN RAT-BRAIN HOMOGENATE

被引：0
|
作者：
HARA, S
ENDO, T
KURIIWA, F
KANO, S
IWATA, N
机构：
来源：
RESEARCH COMMUNICATIONS IN CHEMICAL PATHOLOGY AND PHARMACOLOGY | 1992年 / 76卷 / 03期
关键词：
D O I：
暂无
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
Several calmodulin antagonists, W-7, amitriptyline, trifluoperazine, chlorpromazine, dibucaine, prenylamine, calmidazolium, and compound 48/80, inhibited lipid peroxidation induced non-enzymatically in rat brain homogenate by ascorbate and Fe2+. Suggestions of involvement of calmodulin in various oxidative cellular responses, based on experiments using calmodulin antagonists, may need to be re-evaluated.
引用
收藏
页码：367 / 370
页数：4
相关论文
共 50 条
  • [31] CARBOXYLMETHYLATION OF CALMODULIN INHIBITS CALMODULIN-DEPENDENT PHOSPHORYLATION IN RAT-BRAIN MEMBRANES AND CYTOSOL
    BILLINGSLEY, ML
    VELLETRI, PA
    ROTH, RH
    DELORENZO, RJ
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1983, 258 (09) : 5352 - 5357
  • [32] DISTRIBUTION AND REGULATION OF CALMODULIN MESSENGER-RNAS IN RAT-BRAIN
    GANNON, MN
    MCEWEN, BS
    MOLECULAR BRAIN RESEARCH, 1994, 22 (1-4): : 186 - 192
  • [33] INTERACTION OF TAURINE AND CALMODULIN ON ADRENERGIC-NEURONS IN RAT-BRAIN
    SHIMAZAKI, I
    NOMURA, Y
    SEGAWA, T
    FOLIA PHARMACOLOGICA JAPONICA, 1985, 85 (05) : P51 - P51
  • [34] STEREOCHEMICAL ANALYSIS OF HYDROXYLATED DOCOSAHEXAENOATES PRODUCED BY HUMAN PLATELETS AND RAT-BRAIN HOMOGENATE
    KIM, HY
    KARANIAN, JW
    SHINGU, T
    SALEM, N
    PROSTAGLANDINS & OTHER LIPID MEDIATORS, 1990, 40 (05) : 473 - 490
  • [35] STUDIES OF 4-AMINOBUTYRATE-2-OXOGLUTARATE AMINOTRANSFERASE ON RAT-BRAIN HOMOGENATE
    SOLINAS, SP
    ANTONUCCI, A
    MASSOUD, R
    ITALIAN JOURNAL OF BIOCHEMISTRY, 1984, 33 (05): : A348 - A349
  • [36] CALMODULIN-BINDING PROTEINS IN THE RAT-BRAIN INSOLUBLE FRACTION
    ABE, T
    SAISU, H
    BIOMEDICAL RESEARCH-TOKYO, 1982, 3 (02): : 213 - 218
  • [37] INHIBITION OF CALMODULIN-DEPENDENT ENZYMES IN RAT-BRAIN BY HEXACHLOROCYCLOHEXANE
    BASAVARAJAPPA, BS
    SALIMATH, BP
    PESTICIDE SCIENCE, 1990, 29 (04): : 397 - 404
  • [38] TIGHT-BINDING OF CALMODULIN FRAGMENTS TO RAT-BRAIN NOS
    PERSECHINI, A
    MCMILLAN, K
    LEAKEY, P
    FASEB JOURNAL, 1993, 7 (07): : A1141 - A1141
  • [39] A PROTEIN KINASE-C INHIBITORY ACTIVITY IS PRESENT IN RAT-BRAIN HOMOGENATE
    SCHWANTKE, N
    LEPEUCH, CJ
    FEBS LETTERS, 1984, 177 (01): : 36 - 40
  • [40] HIGH-CONCENTRATIONS OF CALMODULIN ANTAGONISTS INHIBIT ACCUMULATION AND BINDING ACTIVITIES OF [H-3]GLUTAMATE IN RAT-BRAIN
    YONEDA, Y
    OGITA, K
    YAMADA, K
    KOUDA, T
    OHGAKI, T
    UCHIDA, S
    MEGURI, H
    NEUROCHEMISTRY INTERNATIONAL, 1989, 15 (01) : 17 - 23
12345