SYNTHESIS OF 2',3'-DIDEHYDRO-3'-DEOXYTIMIDINE AND ITS ACTIVITY AGAINST HIV

被引：0
|
作者：
TOLSTIKOV, GA [1 ]
MUSTAFIN, AG [1 ]
GATAULLIN, RR [1 ]
ABDRAKHMANOV, IB [1 ]
PLYASUNOVA, OA [1 ]
POKROVSKII, AG [1 ]
机构：
[1] VEKTOR SCI IND ASSOC,KOLTSOV,RUSSIA
来源：
KHIMIYA PRIRODNYKH SOEDINENII | 1993年 / 01期
关键词：
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
引用
收藏
页码：133 / 136
页数：4
相关论文
共 50 条
  • [21] Asymmetrically Substituted myo-Inositols. XXXIX. The Synthesis of Conjugate of 2',3'-Didehydro-3'-deoxythymidine with Phosphatidylinositol: A New Nucleoside Phospholipid with Potential Anti-HIV Activity
    N. S. Shastina
    O. A. Tuchnaya
    L. I. Einisman
    I. I. Kashiricheva
    A. E. Stepanov
    A. M. Yurkevich
    V. I. Shvets
    Russian Journal of Bioorganic Chemistry, 2003, 29 : 267 - 273
  • [22] 2',3'-didehydro-3'-deoxythymidine: Regulation of its metabolic activation by modulators of thymidine-5'-triphosphate biosynthesis
    Ahluwalia, GS
    Gag, WY
    Mitsuya, H
    Johns, DG
    MOLECULAR PHARMACOLOGY, 1996, 50 (01) : 160 - 165
  • [23] PHARMACOKINETICS OF STAVUDINE (2',3'-DIDEHYDRO-3'-DEOXYTHYMIDINE) IN THE NEONATAL MACAQUE (MACACA-NEMESTRINA)
    KELLER, RD
    NOSBISCH, C
    UNADKAT, JD
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1995, 39 (12) : 2829 - 2831
  • [24] Asymmetric synthesis and anti-HIV activity of 1-carbocyclic 2′,3′-didehydro-2′,3′-dideoxyadenosine
    Wang, PY
    Schinazi, RF
    Chu, CK
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1998, 8 (13) : 1585 - 1588
  • [25] Radioimmunoassay for quantitation of 2',3'-didehydro-3'-deoxythymidine (D4T) in human plasma
    Zhou, XJ
    Chakboub, H
    Ferrua, B
    Moravek, J
    Guedj, R
    Sommadossi, JP
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1996, 40 (06) : 1472 - 1475
  • [26] SYNTHESIS AND ANTI-HIV ACTIVITY OF 3'-CYANO-2',3'-DIDEOXYTHYMIDINE AND 3'-CYANO-2',3'-DIDEHYDRO-2',3'-DIDEOXYTHYMIDINE
    MATSUDA, A
    SATOH, M
    NAKASHIMA, H
    YAMAMOTO, N
    UEDA, T
    HETEROCYCLES, 1988, 27 (11) : 2545 - 2548
  • [27] Phosphoramidate protides of carbocyclic 2′,3′-dideoxy-2′,3′-didehydro-7-deazaadenosine with potent activity against HIV and HBV
    Gudmundsson, KS
    Wang, ZC
    Daluge, SM
    Johnson, LC
    Hazen, R
    Condreay, LD
    McGuigan, C
    NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, 2004, 23 (12): : 1929 - 1937
  • [28] Determination of dosing guidelines for stavudine (2′,3′-didehydro-3′-deoxythymidine) in children with human immunodeficiency virus infection
    Kaul, S
    Kline, MW
    Church, JA
    Dunkle, LM
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2001, 45 (03) : 758 - 763
  • [29] Synthesis and Anti-HIV Activity of a Series of 6-Modified 2', 3'-Dideoxyguanosine and 2', 3'-Didehydro-2', 3'-dideoxyguanosine Analogs
    Xie, Lujia
    Yang, Xiantao
    Pan, Delin
    Cao, Yingli
    Cao, Mou
    Lin, Guichun
    Guan, Zhu
    Guo, Ying
    Zhang, Lihe
    Yang, Zhenjun
    CHINESE JOURNAL OF CHEMISTRY, 2013, 31 (09) : 1207 - 1218
  • [30] A HIGHLY STEREOSELECTIVE SYNTHESIS OF ANTI-HIV 2',3'-DIDEOXYNUCLEOSIDES AND 2',3'-DIDEHYDRO-2',3'-DIDEOXYNUCLEOSIDES
    BEACH, JW
    KIM, HO
    JEONG, LS
    NAMPALLI, S
    ISLAM, Q
    AHN, SK
    BABU, JR
    CHU, CK
    JOURNAL OF ORGANIC CHEMISTRY, 1992, 57 (14): : 3887 - 3894
12345