IL-12 enhanced IFN-gamma protein production, NK and LAK cytotoxicity in cord monocyte depleted mononuclear cells (MD-MNC): Potential for immunotherapy post cord blood (CB) transplantation

被引：0

作者：

Suen, Y ^{[1
]}

Chang, L ^{[1
]}

Qian, J ^{[1
]}

Bruner, V ^{[1
]}

Knoppel, E ^{[1
]}

vandeVen, C ^{[1
]}

Cairo, MS ^{[1
]}

机构：

[1] CHILDRENS HOSP ORANGE CTY,ORANGE,CA 92668

来源：

BLOOD | 1995年 / 86卷 / 10期

关键词：

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：3898 / 3898

页数：1

共 32 条

[21] A novel approach for expansion and activation of natural killer cell subsets in previously cryopreserved cord blood (CB) with anti-CD3, IL-2, IL-7 and IL-12: Implication for adoptive cellular immunotherapy post cord blood transplantation (CBT)
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Cairo, MS
[J]. EXPERIMENTAL HEMATOLOGY, 2004, 32 (07) : 77 - 77
[22] Mechanisms of dysregulation of interleukin-12 (IL-12) gene expression in activated cord vs. adult mononuclear cells (MNC): Altered post-transcriptional regulation by labile protein synthesis.
Lee, S
Suen, Y
Cairo, MS
[J]. BLOOD, 1997, 90 (10) : 1617 - 1617
[23] IL-2 PLUS IL-12 ENHANCE NK AND LAK CYTOTOXICITY BUT NOT THE ALLOGENEIC GRAFT-VS-HOST RESPONSE - IMPLICATIONS FOR EX-VIVO AND IN-VIVO APPLICATION POST CORD OR BONE-MARROW TRANSPLANTATION
CHANG, L
BRUNER, V
VANDEVEN, C
CAIRO, MS
[J]. PEDIATRIC RESEARCH, 1995, 37 (04) : A156 - A156
[24] Significant downregulation of interleukin (IL-)-18 gene expression and protein production in constitutive and activated umbilical cord blood (CB) vs. adult peripheral blood (APB) mononuclear cells (MNC): Potential mechanism for differential alloreactivity.
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[J]. BLOOD, 2001, 98 (11) : 205A - 205A
[25] Immaturity of IL-18 gene expression and protein production in cord blood (CB) versus peripheral blood (PB) mononuclear cells and differential effects in natural killer (NK) cell development and function
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Simpson, LL
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Cairo, MS
[J]. BRITISH JOURNAL OF HAEMATOLOGY, 2005, 130 (02) : 284 - 292
[26] Significant downregulation of interleukin (IL)-18 gene expression and protein production and IL-18 induced IFN-γ production in activated cord blood (CB) vs. adult peripheral blood (APB) mononuclear cells (MNC) may be secondary to posttranscriptional dysregulation:: Potential mechanism for differences in CB vs. APB immune reconstitution and aGVHD.
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Cairo, S
van De Ven, C
Suri, M
Baxi, LV
Cairo, MS
[J]. BLOOD, 2002, 100 (11) : 51B - 51B
[27] Ex vivo expansion, maturation, and activation of umbilical cord blood-derived T lymphocytes with IL-2, IL-12, anti-CD3, and IL-7: Potential for adoptive cellular immunotherapy post-umbilical cord blood transplantation
Robinson, KL
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Hughes, R
van de Ven, C
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Cairo, MS
[J]. EXPERIMENTAL HEMATOLOGY, 2002, 30 (03) : 245 - 251
[28] Significant downregulation of interleukin (IL)-18 gene expression and protein production in activated cord blood (CB) vs. adult peripheral blood (APB) mononuclear cells (MNC) may be secondary to posttranscriptional dysregulation: Potential mechanism for differences in CB vs. APBT cell immunity
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van de Ven, C
Suri, M
Baxi, LV
Cairo, MS
[J]. PEDIATRIC RESEARCH, 2003, 53 (04) : 12A - 13A
[29] Dysregulation of interleukin (IL)-18 gene expression and protein production in basal and activated cord blood (CB) vs. peripheral blood (PB) mononuclear cells and differential effects of IL-18 in CB vs. PB T and NK cell immunity
Satwani, P
Ayello, J
Simpson, L
van de Ven, C
Cairo, MS
[J]. BLOOD, 2004, 104 (11) : 727A - 727A
[30] Enhanced natural killer (NK) and NK T cell activation, expansion and cytokine protein production following ex-vivo engineering (EvE) of cryopreserved umbilical cord blood (UCB): Potential role of CBNK and NKT cells in adoptive cellular immunotherapy (ACI)
Ayello, Janet
Satwani, Prakash
De Ven, Carmella Van
Baxi, Laxmi
Wapner, Ronald
Sugarman, Etan
Cairo, Mitchell S.
[J]. BLOOD, 2007, 110 (11) : 365A - 366A

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