KINETIC RESOLUTION OF RACEMIC CARBOXYLIC-ACIDS WITH HOMOCHIRAL ALCOHOLS AND DICYCLOHEXYLCARBODIIMIDE

被引：22
|
作者：
CHINCHILLA, R
NAJERA, C
YUS, M
HEUMANN, A
机构：
[1] UNIV ALICANTE,FAC CIENCIAS,DEPT QUIM ORGAN,E-03690 ALACANT,SPAIN
[2] UNIV AIX MARSEILLE,CTR ST JEROME,ENSSPICAM,URA 1410,F-13013 MARSEILLE,FRANCE
来源：
TETRAHEDRON-ASYMMETRY | 1991年 / 2卷 / 02期
关键词：
D O I：
10.1016/S0957-4166(00)80527-3
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
Racemic carboxylic acids have been kinetically resolved by means of homochiral alcohols using the DCC-esterification methodology. The best results were obtained with commercially available homochiral 1-(4-pyridyl)ethanol: < 60% e.e. for enantiomerically enriched acids and < 76% d.e. for diastereomerically enriched esters.
引用
收藏
页码：101 / 104
页数：4
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