PLATELET ALPHA-2-ADRENERGIC RECEPTOR-BINDING TO H-3 YOHIMBINE AND PERSONALITY VARIATIONS IN NORMALS

被引：4

作者：

SHEKIM, WO

BYLUND, DB

FRANKEL, F

ALEXSON, J

CORCORAN, CM

MCALLISTER, JM

RAYPRENGER, C

机构：

[1] BURBANK UNIFIED SCH DIST,BURBANK,CA

[2] UNIV CALIF LOS ANGELES,CHILD AMBULATORY CARE SERV,LOS ANGELES,CA 90024

[3] UNIV NEBRASKA,MED CTR,COLL MED,DEPT PHARMACOL,OMAHA,NE 68105

[4] UNIV MISSOURI,DEPT PHARMACOL,COLUMBIA,MO 65201

[5] UNIV MISSOURI,DEPT PSYCHIAT,COLUMBIA,MO 65201

来源：

PSYCHIATRY RESEARCH | 1990年 / 32卷 / 02期

关键词：

Minnesota Multiphasic Personality Inventory; norepinephrine; Sensation Seeking Scale; α[!sub]2[!/sub]-Adrenergic receptor;

D O I：

10.1016/0165-1781(90)90078-J

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

The authors examined platelet α2-adrenergic receptor binding to 3H-yohimbine and several personality variables in 58 adult males in a campus community. Subjects with high receptor Bmax levels exhibited personality traits of less social inhibition and more sensation seeking and thrill seeking behavior, were more playful and autonomous, and came from healthier, more intact families. The results also suggested that high affinity states of platelet α2-adrenergic receptors (low Kd) correlate with traits suggestive of stability, i.e., Autonomy, Dominance, Nurturance, Order, Succorance, and General Sensation Seeking Scale of Zuckerman, while low affinity states (high Kd) of platelet α2-receptors correlate with psychopathological traits of Defendence, Exhibitionism, and Paranoia. © 1990.

引用

页码：125 / 134

页数：10

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