A STUDY ON SONODYNAMIC THERAPY ANTITUMOR EFFECT OF NOVEL SONODYNAMIC COMPOUNDS UNDER ULTRASOUND

被引：16
|
作者：
SUZUKI, T [1 ]
KAMADA, S [1 ]
YOSHIDA, Y [1 ]
UNNO, K [1 ]
机构：
[1] AKITA UNIV,COLL MIN,DEPT ELECTR ENGN,TEGATA,AKITA 010,JAPAN
来源：
HETEROCYCLES | 1994年 / 38卷 / 06期
关键词：
D O I：
10.3987/COM-94-6682
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Diacetylhematoporphyrin-mitomycin C conjugate ( diAc-Hp-MMC ) (1) prepared by a condensation of diacetylhematoporphyrin with MMC in the presence of N, N- dimethylaminopyridine and dicyclohexylcarbodiimide, and two of the pyridocarbazole derivatives (8) and (9) were provided for sonodynamic compounds and these compounds were found to show excellent cell-killing effect, comparing to those of the known sonodynamc compound hematoporphyrin, Hp 2HCl (2), Di-Ac-Hp (3), Hp-Co (4), Hp-Fe (5), Acrinol ( 6) and MMC (7).
引用
收藏
页码：1209 / 1211
页数：3
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