SYNTHESIS OF 1,2,3,4-TETRAHYDRO-5H-[1]BENZOPYRANO[3,4-C]PYRIDIN-5-ONES .2. SUBSTITUTION AT THE 3-POSITION WITH 2-AMINOETHYL AND 2-AMINOPROPYL SIDE-CHAINS

被引：9
|
作者：
CONNOR, DT
UNANGST, PC
SCHWENDER, CF
SORENSON, RJ
CARETHERS, ME
PUCHALSKI, C
BROWN, RE
机构：
来源：
JOURNAL OF HETEROCYCLIC CHEMISTRY | 1984年 / 21卷 / 05期
关键词：
D O I：
10.1002/jhet.5570210564
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Methods for the synthesis of 3-[2-aminoethyl]-1,2,3,4-tetrahydro-5H-[1]benzopyrano[3,4-c]pyridin-5-ones and 3-[2-aminopropyl]-1,2,3,4-tetrahydro-5H-[1]benzopyrano[3,4-c]pyridin-5-ones are described. The scope and limitations of the various methods are discussed. [These compounds could be useful in the treatment of asthma and bronchitis.].
引用
收藏
页码：1561 / 1564
页数：4
相关论文
共 50 条
  • [31] IMIDAZOLE DERIVATIVES .2. SYNTHESIS OF IMIDAZO[1,2-A]PYRIDIN-5-ONES
    KNOLKER, HJ
    BOESE, R
    HITZEMANN, R
    HETEROCYCLES, 1989, 29 (08) : 1551 - 1558
  • [32] Synthesis of 3-(2-aminoethyl)-5-hydroxy-1H-pyrazole derivatives
    Groselj, Uros
    Kralj, David
    Wagger, Jernej
    Dahmann, Georg
    Stanovnik, Branko
    Svete, Jurij
    ARKIVOC, 2012, : 49 - 65
  • [33] PROPERTIES OF 4H-[1]BENZOPYRANO[3,4-C][1,2,5]SELENODIAZOL-4-ONE
    SAVELEV, VL
    SAMSONOVA, OL
    TROITSKAYA, VS
    LEZINA, VP
    KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 1991, (01): : 128 - 133
  • [34] [1,2,5]Selenadiazolo[3,4-c][1,2,5]thiadiazole and [1,2,5]Selenadiazolo[3,4-c][1,2,5jthiadiazolidyl -: A synthetic, structural, and theoretical study
    Bagryanskaya, Irina Yu.
    Gatilov, Yuri V.
    Gritsan, Nina P.
    Ikorskii, Vladimir N.
    Irtegova, Irina G.
    Lonchakov, Anton V.
    Lork, Enno
    Mews, Ruediger
    Ovcharenko, Victor I.
    Semenov, Nikolay A.
    Vasilieva, Nadezhda V.
    Zibarev, Andrey V.
    EUROPEAN JOURNAL OF INORGANIC CHEMISTRY, 2007, 30 (30) : 4751 - 4761
  • [35] CERTAIN STEROIDAL (3,4-C)-1',2',5'-OXADIAZOLES
    YADAV, MR
    JINDAL, DP
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 1991, 30 (05): : 473 - 476
  • [36] A facile one-pot synthesis of functionalized 1,5-Dihydro-2H-[1]benzopyrano[2,3-b]pyridin-5-ones
    Esmaeili, Abbas Ali
    Ghareghani, Omid
    HELVETICA CHIMICA ACTA, 2007, 90 (09) : 1712 - 1717
  • [37] STUDIES IN STEROIDAL [3,4-C]-1',2',5'-OXADIAZOLES
    YADAV, MR
    ABRAHAM, J
    JINDAL, DP
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 1990, 29 (01): : 26 - 28
  • [38] Synthesis and SAR of 2,3,3a,4-tetrahydro-1H-pyrrolo[3,4-c]isoquinolin-5(9bH)-ones as 5-HT2C receptor agonists
    Fevig, John M.
    Feng, Jianxin
    Rossi, Karen A.
    Miller, Keith J.
    Wu, Ginger
    Hung, Chen-Pin
    Ung, Thao
    Malmstrom, Sarah E.
    Zhang, Ge
    Keim, William J.
    Cullen, Mary Jane
    Rohrbach, Kenneth W.
    Qu, Qinling
    Gan, Jinping
    Pelleymounter, Mary Ann
    Robl, Jeffrey A.
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2013, 23 (01) : 330 - 335
  • [39] SYNTHESIS OF SPIRO(4H-COUMARINO[3,4-C]-1,2,3,4-TETRAHYDROPYRIDINE(2,2')-2'H-CHROMENE)
    MANDAL, TK
    SOLDATENKOV, AT
    SERGEEVA, ND
    AGEEV, EA
    PROSTAKOV, NS
    ZHURNAL ORGANICHESKOI KHIMII, 1990, 26 (04): : 919 - 920
  • [40] EFFICIENT SYNTHESIS OF CHIRAL 5-METHOXYCARBONYL-PYRIDIN-2(1H)-ONES AND 3-BROMO-5-METHOXYCARBONYL-PYRIDIN-2(1H)-ONES
    Pilotzi, Hugo
    Gnecco, Dino
    Orea, Maria L.
    Aparicio, David M.
    Bernes, Sylvain
    Juarez, Jorge R.
    Teran, Joel L.
    HETEROCYCLES, 2019, 98 (02) : 215 - 223
12345