STRUCTURAL FACTORS AFFECTING CHIRAL RECOGNITION AND SEPARATION ON CELLULOSE BASED CHIRAL STATIONARY PHASES

被引:28
|
作者
ABOULENEIN, HY
ISLAM, MR
机构
[1] Drug Development Laboratory, Radionuclide & Cyclotron Operations Department, King Faisal Specialist Hospital & Research Centre, Riyadh
来源
JOURNAL OF LIQUID CHROMATOGRAPHY | 1990年 / 13卷 / 03期
关键词
D O I
10.1080/01483919008051800
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
The structural factors and functional group selectivity requirements affecting direct high-performance liquid chromatographic enantiomeric resolution of drug racemates on several derivatized cellulose chiral stationary phases are reviewed. A. guide for the choice of the appropriate chiral cellulose derivative column based on elements of asymmetry and functional groups of the compounds are presented. © 1990, Taylor & Francis Group, LLC. All rights reserved.
引用
收藏
页码:485 / 492
页数:8
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