ENTEROBACTERIACAE, PRODUCING ESBLS AND METALLO-beta-LACTAMASE NDM-1, ISOLATED IN HOSPITALS OF BALTIC REGION COUNTRIES

被引:0
|
作者
Egorova, S. A. [1 ]
Kaftyreva, L. A. [1 ]
Lipskaya, L., V [2 ]
Konovalenko, I. B. [3 ]
Pyasetskaya, M. F.
Kurchikova, T. S. [4 ]
Vedernikova, N. B. [5 ]
Morozova, O. T. [6 ]
Smirnova, M., V [7 ]
Popenko, L. N. [8 ]
Lubushkina, M., I
Savochkina, J. A.
Makarova, M. A. [1 ]
Suzhaeva, L., V [1 ]
Ostankova, J., V [1 ,9 ]
Ivanova, M. N.
Pavelkovich, A. M.
Naaber, P. [10 ,11 ]
Sepp, E. [11 ]
Koljalg, S. [11 ]
Miciuleviciene, J. [12 ]
Balode, A. [13 ]
机构
[1] FBUN Res Inst Epidemiol & Microbiol, St Petersburg, Russia
[2] City Clin Hosp 40, St Petersburg, Russia
[3] City Clin Hosp 31, St Petersburg, Russia
[4] City Childrens Hosp 17, St Petersburg, Russia
[5] St George Great Martyr Hosp, St Petersburg, Russia
[6] City Childrens Hosp 1, St Petersburg, Russia
[7] City Mariinsky Hosp, St Petersburg, Russia
[8] Inst Emergency Care, St Petersburg, Russia
[9] FBUN Central Res Inst Epidemiol, Moscow, Russia
[10] Eastern Central Hosp, Tallinn, Estonia
[11] Univ Tartu, Tartu, Estonia
[12] Vilnius City Clinic Hosp, Vilnius, Lithuania
[13] Univ Clin Hosp, Riga, Latvia
来源
INFEKTSIYA I IMMUNITET | 2013年 / 3卷 / 01期
关键词
K; pneumoniae; E; coli; resistance; CTX-M; NDM-1;
D O I
暂无
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
We studied the prevalence of K. pneumoniae and E. coli resistance to extended spectrum cephalosporins and carbapenems, isolated from patients of eight hospitals in St-Petersburg from January to May, 2012. Prevalence of cephalosporin resistant isolates varied in different hospitals: E. coli - from 7,8 to 50%, K. pneumoniae -from 25,4 to 88,4%. Isolates produced extended spectrum beta-lactamases CTX-M, mainly CTX-M-1, also CTX-M-2 and CTX-M-9. Twenty two carbapenem-resistant K. pneumoniae strains (also resistant to other antimicrobials) were isolated in three hospitals. MALDI-TOF MS showed that carbapenem resistance was caused by carbapenemase. Carbapenemases of all isolates belonged to metallo-beta-lactamases according to results of the ROSCO Diagnostica tests. The gene coding production of New Delhi metallo-beta-lactamase (blaNDM-1) were detected in all strains. Our data confirmed that the main cephalosporin resistance mechanism of E. coli. K. pneumoniae in Baltic region (including Russia, St-Petersburg) is CTX-M-1 production. For the first time in Russia K. pneumoniae strains producing metallo-beta-lactamases NDM-1 were isolated in several hospitals of St-Petersburg.
引用
收藏
页码:29 / 36
页数:8
相关论文
共 50 条
  • [31] Complete Genome Sequence of the Clinical Strain Acinetobacter baumannii R2090 Carrying the Chromosomally Encoded Metallo-beta-Lactamase Gene bla(NDM-1)
    Krahn, Thomas
    Wibberg, Daniel
    Maus, Irena
    Winkler, Anika
    Nordmann, Patrice
    Puehler, Alfred
    Poirel, Laurent
    Schlueter, Andreas
    GENOME ANNOUNCEMENTS, 2015, 3 (05)
  • [32] First report of an NDM-1 metallo-β-lactamase-producing Acinetobacter baumannii clinical isolate in Greece
    Voulgari, Evangelia
    Politi, Lida
    Pitiriga, Vassiliki
    Dendrinos, John
    Poulou, Aggeliki
    Georgiadis, George
    Tsakris, Athanassios
    INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2016, 48 (06) : 761 - 762
  • [33] PHT427 as an effective New Delhi metallo-β-lactamase-1 (NDM-1) inhibitor restored the susceptibility of meropenem against Enterobacteriaceae producing NDM-1
    Li, Xiaohui
    Wang, Qian
    Zheng, Ji
    Guan, Yan
    Liu, Chennan
    Han, Jiangxue
    Liu, Sihan
    Liu, Tianjun
    Xiao, Chunling
    Wang, Xiao
    Liu, Yishuang
    FRONTIERS IN MICROBIOLOGY, 2023, 14
  • [34] New Delhi metallo-beta-lactamase 1-producing Enterobacteriaceae: emergence and response in Europe
    Struelens, M. J.
    Monnet, D. L.
    Magiorakos, A. P.
    O'Connor, F. Santos
    Giesecke, J.
    EUROSURVEILLANCE, 2010, 15 (46): : 9 - 16
  • [35] A Case of New Delhi Metallo-β-Lactamase 1 (NDM-1)-Producing Klebsiella pneumoniae with Putative Secondary Transmission from the Balkan Region in the Netherlands
    Halaby, Teysir
    Reuland, Ascelijn E.
    al Naiemi, Nashwan
    Potron, Anais
    Savelkoul, Paul H. M.
    Vandenbroucke-Grauls, Christina M. J. E.
    Nordmann, Patrice
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2012, 56 (05) : 2790 - 2791
  • [36] Emergence of multidrug resistance and metallo-beta-lactamase producing Acinetobacter baumannii isolated from patients in Shiraz, Iran
    Moghadam, M. N.
    Motamedifar, M.
    Sarvari, J.
    Ebrahim-Saraie, Sedigh H.
    Same, Mousavi M.
    Moghadam, F. N.
    ANNALS OF MEDICAL AND HEALTH SCIENCES RESEARCH, 2016, 6 (03) : 162 - 167
  • [37] Isolation and genetic characterization of metallo-beta-lactamase and carbapenamase producing strains of Acinetobacter baumannii from patients at Tehran hospitals
    Shahcheraghi, F.
    Abbasalipour, M.
    Feizabadi, M. M.
    Ebrahimipour, G. H.
    Akbari, N.
    IRANIAN JOURNAL OF MICROBIOLOGY, 2011, 3 (02) : 68 - 74
  • [38] Investigation of NDM metallo-beta-lactamase and CMY-2 AmpC β-lactamase production in Escherichia coli and Enterobacter spp. isolated from human
    Fatemi S.M.
    Shokri D.
    Mohammadi S.
    Koupahi H.
    Comparative Clinical Pathology, 2018, 27 (4) : 1007 - 1015
  • [39] Intrathecal administration of colistin for meningitis due to New Delhi metallo-β-lactamase 1(NDM-1)-producing Klebsiella pneumoniae
    Inamasu, Joji
    Ishikawa, Kiyohito
    Oheda, Motoki
    Nakae, Shunsuke
    Hirose, Yuichi
    Yoshida, Shunji
    JOURNAL OF INFECTION AND CHEMOTHERAPY, 2016, 22 (03) : 184 - 186
  • [40] First case of New Delhi metallo 13-lactamase-1 (NDM-1)-producing Burkholderia cepacia complex in Iran
    Adariani, Alireza Rezaei
    Sokhanvari, Sarvenaz
    Nikbin, Vajihe Sadat
    Hosseinzadeh, Majid
    Khoram, Zahra
    Solgi, Hamid
    HELIYON, 2024, 10 (10)