ESTIMATION OF XIPAMIDE BY USING HPLC IN PURE AND PHARMACEUTICAL DOSAGE FORM

被引：1
|
作者：
Rajendran, Rameshpetchi [1 ]
Devikasubramaniyan [1 ]
Sura, Ramya Sri [2 ]
Kumar, A. Arun [1 ]
Mounika, A. [1 ]
Sowjanya, A. [1 ]
Priyanka, B. [1 ]
机构：
[1] Bomma Inst Pharm, Khammam 507318, Telangana, India
[2] Osmania Univ, Univ Technol, Hyderabad 500007, Telangana, India
来源：
INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES | 2018年 / 5卷 / 04期
关键词：
Xipamide; RP-HPLC; validation;
D O I：
10.5281/zenodo.1214540
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
A rapid and precise Reverse Phase High Performance Liquid Chromatographic method has been developed for the validated of Xipamide in its pure form as well as in tablet dosage form. Chromatography was carried out on Symmetry C18 (4.6x150 mm, 5 mu) column using a mixture of Acetonitrile:Water (50:50v/v)as the mobile phase at a flow rate of 1.0ml/min, the detection was carried out at 245nm. The retention time of the Xipamide was 2.4 +/- 0.02min. The method produce linear responses in the concentration range of 10-50 mu g/ml of Xipamide. The method precision for the determination of assay was below 2.0%RSD. The method is useful in the quality control of bulk and pharmaceutical formulations.
引用
收藏
页码：2095 / 2102
页数：8
相关论文
共 50 条
  • [21] HPLC Analysis of Urapidil in Pharmaceutical Dosage Form
    Cai, Defu
    Zhang, Qi
    ASIAN JOURNAL OF CHEMISTRY, 2012, 24 (01) : 315 - 318
  • [22] Estimation of Metaxalone in Pure and Tablet Dosage Form by RP-HPLC Method
    Balaji, M.
    Nagavalli, D.
    Vetrichelvan, T.
    INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2009, 71 (02) : 190 - 191
  • [23] Optimization of Stability Indicating RP-HPLC method for The Estimation of an Antidepressant Agents Alprazolam and Imipramine in Pure & Pharmaceutical Dosage Form
    Chauhan, Payal P.
    Patel, Divya Y.
    Shah, Samir K.
    EURASIAN JOURNAL OF ANALYTICAL CHEMISTRY, 2016, 11 (02): : 101 - 113
  • [24] Development and validation of stability indicating RP-HPLC method for the simultaneous estimation of linagliptin and metformin in pure and pharmaceutical dosage form
    Kavitha, K.Y.
    Geetha, G.
    Hariprasad, R.
    Kaviarasu, M.
    Venkatnarayanan, R.
    Journal of Chemical and Pharmaceutical Research, 2013, 5 (01) : 230 - 235
  • [25] Quantitative bioanalytical and analytical methods for estimation of ivabradine hydrochloride in pure and pharmaceutical dosage form
    Polker, Anjali
    Padmavathi, Yenumula
    Kumar, Ravi
    Babu, Nayaka Raghavendra
    JOURNAL OF REPORTS IN PHARMACEUTICAL SCIENCES, 2020, 9 (01): : 1 - 10
  • [26] RP- HPLC Method for Estimation of Atomoxetine Hydrochloride in Bulk and Pharmaceutical Dosage Form
    Lakshmi, G. Teja
    Rao, Y. Srinivasa
    Rao, K. Vara Prasada
    Kumar, T. Hemant
    RESEARCH JOURNAL OF PHARMACEUTICAL BIOLOGICAL AND CHEMICAL SCIENCES, 2015, 6 (02): : 1208 - 1214
  • [27] SIMULTANEOUS ESTIMATION OF HYDROCORTISONE AND KETOCONAZOLE IN PHARMACEUTICAL DOSAGE FORM BY RP-HPLC METHOD
    Naik, Ramavath Mohanbabu
    Gumpula, Swapna
    Mhaskar, Prajakta Shamsundar
    INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH, 2018, 9 (11): : 4805 - 4811
  • [28] RP-HPLC PDA METHOD FOR ESTIMATION OF PRULIFLOXACIN IN BULK AND PHARMACEUTICAL DOSAGE FORM
    Rajendran, Rameshpetchi
    Devikasubramaniyan
    Sura, Ramya Sri
    Veeranna, E.
    Chandraprabha, G.
    Kiranmai, G.
    Tharunkumar, G.
    INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2018, 5 (04): : 2088 - 2094
  • [29] Development of RP-HPLC Method for the Estimation of Rabeprazole in Pure and Tablet Dosage Form
    Rao, A. Lakshmana
    Kumar, B. N. V. Ravi
    Sankar, G. G.
    E-JOURNAL OF CHEMISTRY, 2008, 5 : 1149 - 1153
  • [30] An eco-friendly micellar HPLC method for the simultaneous determination of triamterene and xipamide in active pharmaceutical ingredients and marketed tablet dosage form
    Ayad, Magda M.
    Hosny, Mervat M.
    Ibrahim, Adel Ehab
    El-Abassy, Omar M.
    Belal, Fathalla F.
    ACTA CHROMATOGRAPHICA, 2021, 33 (01) : 51 - 56
12345