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- [1] ANTITUMOR IMIDAZOTETRAZINES .1. SYNTHESIS AND CHEMISTRY OF 8-CARBAMOYL-3-(2-CHLOROETHYL)IMIDAZO[5,1-D]-1,2,3,5-TETRAZIN-4(3H)-ONE, A NOVEL BROAD-SPECTRUM ANTITUMOR AGENTJOURNAL OF MEDICINAL CHEMISTRY, 1984, 27 (02) : 196 - 201STEVENS, MFGHICKMAN, JASTONE, RGIBSON, NWBAIG, GULUNT, ENEWTON, CG
- [2] EFFECTS OF THE ANTITUMOR AGENT 8-CARBAMOYL-3-(2-CHLOROETHYL)IMIDAZO[5,1-D]-1,2,3,5-TETRAZIN-4(3H)-ONEON THE DNA OF MOUSE L1210 CELLSCANCER RESEARCH, 1984, 44 (05) : 1767 - 1771GIBSON, NWERICKSON, LCHICKMAN, JA
- [3] ANTITUMOR IMIDAZOTETRAZINES .6. EXPERIMENTAL ANTITUMOR-ACTIVITY AGAINST MURINE TUMOR-MODEL SYSTEMS OF 8-CARBAMOYL-3-(2-CHLOROETHYL)IMIDAZO[5,1-D]-1,2,3,5-TETRAZIN-4(3H)-ONE(MITOZOLOMIDE), A NOVEL BROAD-SPECTRUM AGENTCANCER RESEARCH, 1985, 45 (07) : 3008 - 3013HICKMAN, JASTEVENS, MFGGIBSON, NWLANGDON, SPFIZAMES, CLAVELLE, FATASSI, GLUNT, ETILSON, RM
- [4] ANTITUMOR IMIDAZOTETRAZINES .25. CRYSTAL-STRUCTURE OF 8-CARBAMOYL-3-METHYLIMIDAZO[5,1-D]-1,2,3,5-TETRAZIN-4(3H)-ONE (TEMOZOLOMIDE) AND STRUCTURAL COMPARISONS WITH THE RELATED DRUGS MITOZOLOMIDE AND DTICJOURNAL OF MEDICINAL CHEMISTRY, 1992, 35 (18) : 3377 - 3382LOWE, PRSANSOM, CESCHWALBE, CHSTEVENS, MFGCLARK, AS
- [5] DNA CROSS-LINKING AND CYTO-TOXICITY IN NORMAL AND TRANSFORMED HUMAN-CELLS TREATED INVITRO WITH 8-CARBAMOYL-3-(2-CHLOROETHYL)IMIDAZO[5,1-D]-1,2,3,5-TETRAZIN-4(3H)-ONECANCER RESEARCH, 1984, 44 (05) : 1772 - 1775GIBSON, NWHICKMAN, JAERICKSON, LC
- [7] REACTIONS WITH DIAZOAZOLES .8. SYNTHESES OF AZOLO[5,1-D]-1,2,3,5-TETRAZIN-4(3H)-ONESCHEMISCHE BERICHTE-RECUEIL, 1987, 120 (08): : 1375 - 1395EGE, GGILBERT, KMAURER, K
- [8] Antitumour imidazotetrazines.: Part 36.: Conversion of 5-aminoimidazole-4-carboxamide to imidazo[5,1-d][1,2,3,5]tetrazin-4(3H)-ones and imidazo[1,5-a][1,3,5]triazin-4(3H)-ones related in structure to the antitumour agents temozolomide and mitozolomideJOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1998, (10): : 1669 - 1675Wang, YFWheelhouse, RTZhao, LXLangnel, DAFStevens, MFG
- [10] ANTITUMOR IMIDAZOTETRAZINES .13. ANTITUMOR-ACTIVITY AND PHARMACOKINETICS IN MICE OF 8-CARBAMOYL-3-METHYL-IMIDAZO[5,1-D]-1,2,3,5-TETRAZIN-4(3H)-ONE (CCRG 81045-M-AND-B-39831), A NOVEL DRUG WITH POTENTIAL AS AN ALTERNATIVE TO DACARBAZINECANCER RESEARCH, 1987, 47 (22) : 5846 - 5852STEVENS, MFGHICKMAN, JALANGDON, SPCHUBB, DVICKERS, LSTONE, RBAIG, GGODDARD, CGIBSON, NWSLACK, JANEWTON, CLUNT, EFIZAMES, CLAVELLE, F