DETERMINATION OF ASCORBIC-ACID IN PHARMACEUTICALS AND URINE BY REVERSE FLOW-INJECTION

被引：15
|
作者：
ALBERO, MI [1 ]
GARCIA, MS [1 ]
SANCHEZPEDRENO, C [1 ]
RODRIGUEZ, J [1 ]
机构：
[1] UNIV MURCIA,FAC CHEM,DEPT ANALYT CHEM,MURCIA,SPAIN
来源：
ANALYST | 1992年 / 117卷 / 10期
关键词：
ASCORBIC ACID; ETHYLENEDIAMINETETRAACETIC ACID-COBALT(III) COMPLEX; FLOW INJECTION; PHARMACEUTICALS; URINE;
D O I：
10.1039/an9921701635
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Two reverse flow injection (FI) methods, using spectrophotometric detection, are proposed for the determination of ascorbic acid. Both methods are based on its reaction with the ethylenediaminetetraacetic acid-Co(III) complex in a medium of 5% diethylamine. In the first method, using the peak-height FI technique, ascorbic acid is determined over the range from 2 x 10(-4) to 5 x 10(-3) mol dm-3 and in the second, using the peak-width FI method, the working range is extended (2 x 10(-3)-5 x 10(-2) Mol dm-3). Both FI methods were applied to the determination of ascorbic acid in pharmaceuticals while the peak-height FI technique was also used to determine ascorbic acid in urine.
引用
收藏
页码：1635 / 1638
页数：4
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