Concurrent crizotinib and whole-brain radiation for brain metastases in ALK-positive lung adenocarcinoma

被引：0
|
作者：
Pinto, Ian G. [1 ]
Lee, Mijung [1 ]
Graziano, Stephen [1 ]
Lacombe, Michael [1 ]
Gajra, Ajeet [1 ]
机构：
[1] SUNY Upstate Med Univ, 750 E Adams St, Syracuse, NY 13210 USA
来源：
LUNG CANCER MANAGEMENT | 2014年 / 3卷 / 05期
关键词：
ALK; concurrent crizotinib radiation; crizotinib; lung cancer; oral-targeted therapy; radiation;
D O I：
10.2217/LMT.14.28
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
Crizotinib is now used for ALK-positive adenocarcinoma of the lung. To the best of our knowledge it has not been used concurrently with radiation. We report the first case where a patient safely tolerated crizotinib with concurrent whole-brain radiation therapy for brain metastases in ALK-positive adenocarcinoma of the lung. The patient had a good response to the combination with improved performance status.
引用
收藏
页码：369 / 371
页数：3
相关论文
共 50 条
  • [31] Combination of crizotinib and radiation in the treatment of ALK-positive and cetuximab-resistant lung cancer
    Li, Chunrong
    Huang, Shyhmin
    Walters, Noah
    Armstrong, Eric A.
    Harari, Paul M.
    CANCER RESEARCH, 2014, 74 (19)
  • [32] Alectinib for the management of ALK-positive non-small cell lung cancer brain metastases
    Lockney, Natalie A.
    Wu, Abraham J.
    JOURNAL OF THORACIC DISEASE, 2017, 9 (02) : E152 - E154
  • [33] Comparison of Whole-Brain Integral Dose Between Whole-Brain Radiation Therapy and Stereotactic Radiosurgery of Multiple Brain Metastases
    White, E. C.
    Wang, R.
    Rahimian, J.
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2014, 90 : S908 - S908
  • [34] Ensartinib rapidly relieves symptoms in ALK-positive patients with brain metastases
    Xu, Hongyan
    Chen, Tingting
    Zheng, Yan
    Fang, Wenzheng
    ASIAN JOURNAL OF SURGERY, 2024, 47 (09) : 3947 - 3949
  • [35] Crizotinib versus Chemotherapy in Advanced ALK-Positive Lung Cancer
    Shaw, Alice T.
    Kim, Dong-Wan
    Nakagawa, Kazuhiko
    Seto, Takashi
    Crino, Lucio
    Ahn, Myung-Ju
    De Pas, Tommaso
    Besse, Benjamin
    Solomon, Benjamin J.
    Blackhall, Fiona
    Wu, Yi-Long
    Thomas, Michael
    O'Byrne, Kenneth J.
    Moro-Sibilot, Denis
    Camidge, D. Ross
    Mok, Tony
    Hirsh, Vera
    Riely, Gregory J.
    Iyer, Shrividya
    Tassell, Vanessa
    Polli, Anna
    Wilner, Keith D.
    Jaenne, Pasi A.
    NEW ENGLAND JOURNAL OF MEDICINE, 2013, 368 (25): : 2385 - 2394
  • [36] Crizotinib versus chemotherapy in advanced ALK-positive lung cancer
    Thibault, Constance
    Teixeira, Luis
    ONCOLOGIE, 2013, 15 (09) : 494 - 495
  • [37] First-Line Crizotinib in ALK-Positive Lung Cancer
    Tural, Deniz
    Kilickap, Saadettin
    NEW ENGLAND JOURNAL OF MEDICINE, 2015, 372 (08): : 781 - 781
  • [38] Efficacy of erlotinib plus concurrent whole-brain radiation therapy for patients with brain metastases from non-small cell lung cancer
    Koizumi, Tomonobu
    Sasaki, Shigeru
    Sakamoto, Akiyuki
    Kobayashi, Takashi
    ANNALS OF PALLIATIVE MEDICINE, 2013, 2 (03) : 111 - 113
  • [39] The role of whole-brain radiation therapy after stereotactic radiation surgery for brain metastases
    Hasan, Shaakir
    Shah, Ashish H.
    Bregy, Amade
    Albert, Trevine
    Markoe, Arnold
    Stoyanova, Radka
    Thambuswamy, Michael
    Komotar, Ricardo J.
    PRACTICAL RADIATION ONCOLOGY, 2014, 4 (05) : 306 - 315
  • [40] Concurrent capecitabine and whole-brain radiotherapy for treatment of brain metastases in breast cancer patients
    Cyrus Chargari
    Youlia M. Kirova
    Véronique Diéras
    Pablo Castro Pena
    Francois Campana
    Paul H. Cottu
    JeanYves Pierga
    Alain Fourquet
    Journal of Neuro-Oncology, 2009, 93 (3) : 385 - 385
12345