Concurrent crizotinib and whole-brain radiation for brain metastases in ALK-positive lung adenocarcinoma

被引：0
|
作者：
Pinto, Ian G. [1 ]
Lee, Mijung [1 ]
Graziano, Stephen [1 ]
Lacombe, Michael [1 ]
Gajra, Ajeet [1 ]
机构：
[1] SUNY Upstate Med Univ, 750 E Adams St, Syracuse, NY 13210 USA
来源：
LUNG CANCER MANAGEMENT | 2014年 / 3卷 / 05期
关键词：
ALK; concurrent crizotinib radiation; crizotinib; lung cancer; oral-targeted therapy; radiation;
D O I：
10.2217/LMT.14.28
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
Crizotinib is now used for ALK-positive adenocarcinoma of the lung. To the best of our knowledge it has not been used concurrently with radiation. We report the first case where a patient safely tolerated crizotinib with concurrent whole-brain radiation therapy for brain metastases in ALK-positive adenocarcinoma of the lung. The patient had a good response to the combination with improved performance status.
引用
收藏
页码：369 / 371
页数：3
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