SYNTHESIS OF 3'-FUNCTIONALIZED OLIGONUCLEOTIDES ON A SINGLE SOLID SUPPORT

被引:14
|
作者
HOVINEN, J [1 ]
GUZAEV, A [1 ]
AZHAYEV, A [1 ]
LONNBERG, H [1 ]
机构
[1] UNIV TURKU,DEPT CHEM,SF-20500 TURKU,FINLAND
关键词
D O I
10.1016/S0040-4039(00)61482-X
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Oligodeoxyribonucleotides tethered with an amino-, carboxy-, amidocarbonyl-, or mercaptoalkyl spacer arm at 3'-terminus were obtained by assembling the chains on a modified aminoalkyl-CPG (1) and releasing them with appropriate reagents.
引用
收藏
页码:8169 / 8172
页数:4
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