A review on synthesis and biological screening of oxazepinedione derivatives

被引：0
|
作者：
Joseph, Lincy [1 ]
George, Mathew [2 ]
Alexander, Anila K. [2 ]
机构：
[1] Pushpagiri Coll Pharm, Dept Pharmaceut Chem, Thiruvalla, Kerala, India
[2] Pushpagiri Coll Pharm, Dept Pharmacol, Thiruvalla, Kerala, India
来源：
BIOINTERFACE RESEARCH IN APPLIED CHEMISTRY | 2016年 / 6卷 / 02期
关键词：
Oxazepinedione; schiff base; phthalic anhydride; maleic anhydride; succinic anhydride; haloacids;
D O I：
暂无
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
At present a number of drugs with various mechanism of action are available for the pharmacotherapy of psychopharmacological disorders. Among them, the most important are dibenzoxazepine and benzodiazepine derivatives. Important drugs contain oxazepine rings are amoxapine and loxapine which are used as typical antipsychotic agents. Oxazepines are seven membered heterocyclic compounds which contribute to various important activities. Nowadays a wide variety of Oxazepinediones derivatives are synthesized and biologically screened for anticancer, antimicrobial and enzymatic activities etc. Oxazepinediones are commonly synthesized by cycloaddition reaction with schiff base and various anhydride (phthalic anhydride/maleic anhydride/succinic anhydride) or haloacids.
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收藏
页码：1137 / 1143
页数：7
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