STUDIES ON THE ANTITUMOR 2,6-PIPERAZINEDIONES - SYNTHESIS OF 2,3-DIACETOXY-4-CARBOMETHOXY-(3',5'-DIOXO-N-4' SUBSTITUTED PIPERAZINYL METHYL) BENZENE

被引：0

作者：

LI, Q

SHAO, HW

JIANG, HL

XIE, YY

机构：

来源：

PHARMAZIE | 1995年 / 50卷 / 07期

关键词：

D O I：

暂无

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The title compounds having the structure of 2,3-diacetoxy-4-carbomethoxy-(3',5'-dioxo-N-4'-substituted piperazinyl methyl) benzene were synthesized from 2-hydroxy-3-methoxybenzaldehyde in eight steps. Compound 9h showed a potent inhibitory effect against P388 leukemia cells in vitro.

引用

页码：447 / 449

页数：3

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