STUDIES ON THE ANTITUMOR 2,6-PIPERAZINEDIONES - SYNTHESIS OF 2,3-DIACETOXY-4-CARBOMETHOXY-(3',5'-DIOXO-N-4' SUBSTITUTED PIPERAZINYL METHYL) BENZENE

被引：0
|
作者：
LI, Q
SHAO, HW
JIANG, HL
XIE, YY
机构：
来源：
PHARMAZIE | 1995年 / 50卷 / 07期
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D O I：
暂无
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The title compounds having the structure of 2,3-diacetoxy-4-carbomethoxy-(3',5'-dioxo-N-4'-substituted piperazinyl methyl) benzene were synthesized from 2-hydroxy-3-methoxybenzaldehyde in eight steps. Compound 9h showed a potent inhibitory effect against P388 leukemia cells in vitro.
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页码：447 / 449
页数：3
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