INHIBITION OF GLYCINE N-METHYLTRANSFERASE ACTIVITY BY FOLATE DERIVATIVES - IMPLICATIONS FOR REGULATION OF METHYL-GROUP METABOLISM

被引：150
|
作者：
WAGNER, C [1 ]
BRIGGS, WT [1 ]
COOK, RJ [1 ]
机构：
[1] VET ADM MED CTR,RES SERV,NASHVILLE,TN 37203
来源：
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1985年 / 127卷 / 03期
关键词：
D O I：
10.1016/S0006-291X(85)80006-1
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：746 / 752
页数：7
相关论文
共 50 条
  • [41] Inhibition of natural killer cells protects the liver against acute injury in the absence of glycine N-methyltransferase
    Gomez-Santos, Laura
    Luka, Zigmund
    Wagner, Conrad
    Fernandez-Alvarez, Sara
    Lu, Shelly C.
    Mato, Jose M.
    Martinez-Chantar, Maria L.
    Beraza, Naiara
    HEPATOLOGY, 2012, 56 (02) : 747 - 759
  • [42] INHIBITION OF PHENYLETHANOLAMINE N-METHYLTRANSFERASE BY BENZYLAMINES .1. STRUCTURE-ACTIVITY RELATIONSHIPS
    FULLER, RW
    MOLLOY, BB
    DAY, WA
    ROUSH, BW
    MARSH, MM
    JOURNAL OF MEDICINAL CHEMISTRY, 1973, 16 (02) : 101 - 106
  • [43] Impaired VLDL secretion and metabolism are related to non-alcoholic steatohepatitis in glycine N-methyltransferase deficient mice
    Martinez-Una, Maite
    Cano, Ainara
    Menor-Mendia, Ariane
    Buque, Xabier
    Maria Mato, Jose
    Vazquez-Chantada, Mercedes
    Luz Martinez-Chantar, Maria
    Ochoa, Begona
    Aspichueta, Patricia
    CHEMISTRY AND PHYSICS OF LIPIDS, 2010, 163 : S65 - S65
  • [44] Benzo[a]pyrene effects on glycine N-methyltransferase mRNA expression and enzyme activity in Fundulus heteroclitus embryos
    Fang, Xiefan
    Dong, Wu
    Thornton, Cammi
    Willett, Kristine L.
    AQUATIC TOXICOLOGY, 2010, 98 (02) : 130 - 138
  • [45] Genetic Variants in Phosphatidylethanolamine N-methyltransferase and Methylenetetrahydrofolate Dehydrogenase Influence Biomarkers of Choline Metabolism When Folate Intake Is Restricted
    Ivanov, Alexandre
    Nash-Barboza, Susan
    Hinkis, Sabrina
    Caudill, Marie A.
    JOURNAL OF THE AMERICAN DIETETIC ASSOCIATION, 2009, 109 (02) : 313 - 318
  • [46] INHIBITION OF HISTAMINE N-METHYLTRANSFERASE ACTIVITY IN GUINEA-PIG PULMONARY ALVEOLAR MACROPHAGES BY NICOTINE
    GAIROLA, C
    GODIN, CS
    HOUDI, AA
    CROOKS, PA
    JOURNAL OF PHARMACY AND PHARMACOLOGY, 1988, 40 (10) : 724 - 726
  • [47] METABOLISM OF S-ADENOSYLMETHIONINE IN RAT HEPATOCYTES - TRANSFER OF METHYL-GROUP FROM S-ADENOSYLMETHIONINE BY METHYLTRANSFERASE REACTIONS
    TSUKADA, K
    ABE, T
    KUWAHATA, T
    MITSUI, K
    LIFE SCIENCES, 1985, 37 (07) : 665 - 672
  • [48] A Novel Tumor Suppressor Function of Glycine N-Methyltransferase Is Independent of Its Catalytic Activity but Requires Nuclear Localization
    DebRoy, Suchandra
    Kramarenko, Inga I.
    Ghose, Sampa
    Oleinik, Natalia V.
    Krupenko, Sergey A.
    Krupenko, Natalia I.
    PLOS ONE, 2013, 8 (07):
  • [49] ROLE OF CENTRAL PHENYL ETHANOLAMINE N-METHYLTRANSFERASE ACTIVITY IN BLOOD-PRESSURE REGULATION IN SHR
    YAMORI, Y
    FUJIWARA, M
    TANASE, H
    HORIE, R
    LOVENBERG, W
    JAPANESE HEART JOURNAL, 1981, 22 (03): : 511 - 511
  • [50] INHIBITORS OF INDOLEETHYLAMINE N-METHYLTRANSFERASE - DERIVATIVES OF 3-METHYL-2-THIAZOLIDINIMINE - INVITRO, INVIVO, AND METABOLIC STUDIES
    ROKACH, J
    GIRARD, Y
    HAMEL, P
    READER, G
    ROONEY, CS
    MANDEL, LR
    CRAGOE, EJ
    ZACCHEI, AG
    JOURNAL OF MEDICINAL CHEMISTRY, 1980, 23 (07) : 773 - 780
12345