PARADOXICAL SLEEP-DEPRIVATION INCREASES GLUTAMINE-SYNTHETASE IN RAT-BRAIN

被引：0
|
作者：
SALLANON, M
TOURET, M
DIDIERBAZES, M
BELIN, MF
TARDY, M
JOUVET, M
机构：
[1] UFR ALEXIS CARREL,INSERM,CJF 9010,ANAT PATHOL LAB,F-69008 LYON,FRANCE
[2] HOP HENRI MONDOR,INSERM,U282,F-94010 CRETEIL,FRANCE
来源：
COMPTES RENDUS DE L ACADEMIE DES SCIENCES SERIE III-SCIENCES DE LA VIE-LIFE SCIENCES | 1992年 / 315卷 / 03期
关键词：
D O I：
暂无
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
The modifications of glutamine synthetase (GS) level, an enzyme mainly located in astrocytes, were investigated in rat after paradoxical sleep deprivation and during recovery. An immunotitration method was used to evaluate the relative level of GS in brain tissue. At the end of a 24 hrs. paradoxical sleep deprivation, a significant increase in GS level was observed both in the frontoparietal cortex and the locus coeruleus area. 4 hrs. later, during recovery, the GS level returned to control level in the cortex but was lower in the locus coeruleus area.
引用
收藏
页码：109 / 114
页数：6
相关论文
共 50 条
  • [21] EFFECTS OF SLEEP-DEPRIVATION ON FOS-LIKE IMMUNOREACTIVITY IN THE RAT-BRAIN
    POMPEIANO, M
    CIRELLI, C
    TONONI, G
    ARCHIVES ITALIENNES DE BIOLOGIE, 1992, 130 (04): : 325 - 335
  • [22] EFFECTS OF CHRONIC SLEEP-DEPRIVATION ON CENTRAL CHOLINERGIC RECEPTORS IN RAT-BRAIN
    TSAI, LL
    BERGMANN, BM
    PERRY, BD
    RECHTSCHAFFEN, A
    BRAIN RESEARCH, 1994, 642 (1-2) : 95 - 103
  • [23] GLUTAMINE-METABOLISM IN EMBRYONIC RAT-BRAIN OF MATERNAL HYPERPHENYLALANINEMIA - WITH SPECIAL REFERENCE TO GLUTAMINE-SYNTHETASE ACTIVITY
    HARADA, S
    IWASAKI, N
    KANAMATSU, T
    ASOU, H
    HIRANO, S
    NOGUCHI, T
    NEUROCHEMICAL RESEARCH, 1984, 9 (08) : 1148 - 1148
  • [24] AGE-RELATED-CHANGES IN GLUTAMINE-SYNTHETASE ACTIVITY OF RAT-BRAIN, LIVER AND HEART
    DANH, HC
    BENEDETTI, MS
    DOSTERT, P
    GERONTOLOGY, 1985, 31 (02) : 95 - 100
  • [25] ACUTE AND LONG-TERM EFFECTS OF CHLORPROMAZINE ON GLUTAMINE-SYNTHETASE AND GLUTAMINASE IN RAT-BRAIN
    CHANDRAKALA, MV
    MARCUS, SR
    NADIGER, HA
    SADASIVUDU, B
    JOURNAL OF NEUROCHEMISTRY, 1987, 49 (01) : 32 - 34
  • [26] EFFECT OF PARADOXICAL SLEEP-DEPRIVATION ON DNA-SYNTHESIS IN FETAL-RAT BRAIN
    GRASSIZUCCONI, G
    BELIA, S
    FRANCIOLINI, F
    MENICHINI, E
    GIUDITTA, A
    INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE, 1984, 2 (06) : 585 - 590
  • [27] REPEATED ADMINISTRATION OF GAMMA-VINYLGABA REDUCES RAT-BRAIN GLUTAMINE-SYNTHETASE ACTIVITY
    WANIEWSKI, RA
    MARTIN, DL
    JOURNAL OF NEUROCHEMISTRY, 1995, 65 (01) : 355 - 362
  • [28] EFFECTS OF CHRONIC TOTAL SLEEP-DEPRIVATION ON CENTRAL NORADRENERGIC RECEPTORS IN RAT-BRAIN
    TSAI, LL
    BERGMANN, BM
    PERRY, BD
    RECHTSCHAFFEN, A
    BRAIN RESEARCH, 1993, 602 (02) : 221 - 227
  • [29] SLEEP-DEPRIVATION - EFFECTS ON CIRCADIAN-RHYTHMS OF RAT-BRAIN NEUROTRANSMITTER RECEPTORS
    WIRZJUSTICE, A
    TOBLER, I
    KAFKA, MS
    NABER, D
    MARANGOS, PJ
    BORBELY, AA
    WEHR, TA
    PSYCHIATRY RESEARCH, 1981, 5 (01) : 67 - 76
  • [30] SEROTONIN BINDING IN RAT-BRAIN - CIRCADIAN-RHYTHM AND EFFECT OF SLEEP-DEPRIVATION
    WESEMANN, W
    WEINER, N
    ROTSCH, M
    SCHULZ, E
    JOURNAL OF NEURAL TRANSMISSION, 1983, : 287 - 294
12345