HIGHLY REGIOSELECTIVE AND STEREOSELECTIVE PREPARATION OF Z-SILYL ENOL ETHERS AND Z-ENOL ESTERS FROM KETONES VIA MANGANESE ENOLATES

被引：19
|
作者：
CAHIEZ, G
FIGADERE, B
CLERY, P
机构：
[1] Laboratoire de Chimie des Organoéléments, associé au CNRS Université P. et M. Curie, F-75252 Paris Cédex 05
来源：
TETRAHEDRON LETTERS | 1994年 / 35卷 / 34期
关键词：
D O I：
10.1016/S0040-4039(00)73415-0
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Mn-enolates are easily and quantitatively obtained under mild conditions (THF, -10 degrees C to rt, 1h) by treatment of ketones with aromatic Mn-amides such as Ph(Me)NMnZ. They allow to prepare Z silyl enol ethers and Z enol esters in high yields and with an excellent regio- and stereoselectivity (kinetic product: greater than or equal to 99%, Z/E: 93/7 to 100/0).
引用
收藏
页码：6295 / 6298
页数：4
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