HIGHLY REGIOSELECTIVE MONOALKYLATION OF KETONES VIA MANGANESE ENOLATES PREPARED FROM MANGANESE AMIDES

被引：19
|
作者：
CAHIEZ, G
FIGADERE, B
CLERY, P
机构：
[1] Laboratoire de Chimie des Organoéléments, associé au CNRS Université P. et M. Curie, F-75252 Paris Cédex 05
来源：
TETRAHEDRON LETTERS | 1994年 / 35卷 / 19期
关键词：
D O I：
10.1016/S0040-4039(00)76829-8
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Ketones are regioselectively converted to Mn-enolates by treatment with Mn-amides such as Ph(Me)NMnCl in THF at 20 degrees C. Mn-enolates can then be regioselectively monoalkylated in good yields. The formation of di or polyalkylated products is never observed (< 1%).
引用
收藏
页码：3065 / 3068
页数：4
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