STYRENE-7,8-OXIDE IN BLOOD OF WORKERS EXPOSED TO STYRENE

被引:34
|
作者
KORN, M [1 ]
GFRORER, W [1 ]
FILSER, JG [1 ]
KESSLER, W [1 ]
机构
[1] GSF,INST TOXICOL,D-85758 OBERSCHLEISSHEIM,GERMANY
关键词
STYRENE; STYRENE-7,8-OXIDE; BLOOD CONCENTRATION; MAN; FIELD STUDY; CAPILLARY GAS CHROMATOGRAPHY;
D O I
10.1007/s002040050107
中图分类号
R99 [毒物学(毒理学)];
学科分类号
100405 ;
摘要
A field study was carried out on 13 workers exposed to styrene vapors at time-weighted average concentrations between 10 and 73 ppm. The reactive intermediate styrene-7,8-oxide was determined in blood samples using a direct gas chromatographic method. Styrene-7,8-oxide concentrations were in the range between 0.9 and 4.1 mu/l blood. Linear correlations were found between styrene-7,8-oxide in blood and styrene in ambient air and blood. For an exposure concentration of 20 ppm styrene (German MAK value) a steady-state level of about 1 mu g styrene-7,8-oxide/l blood was calculated.
引用
收藏
页码:524 / 527
页数:4
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