Before it crumbles: Fulminant Hepatic Failure secondary to Hodgkin's Lymphoma

被引:6
|
作者
Karmacharya, Paras [1 ]
Bhandari, Naresh [2 ]
Aryal, Madan R. [1 ]
Pandit, Aashrayata A. [3 ]
Pathak, Ranjan [1 ]
Ghimire, Sailu [4 ]
Shrestha, Pragya [5 ]
Bhatt, Vijaya R. [6 ]
机构
[1] Reading Hlth Syst, Dept Internal Med, 6th Ave & Spruce St, W Reading, PA 19612 USA
[2] St Agnes Hosp, Dept Internal Med, Baltimore, MD USA
[3] Mayo Clin, Div Cardiovasc Dis, Scottsdale, AZ USA
[4] Coll Med Sci, Dept Internal Med, Bharatpur, Nepal
[5] Nanjing Med Univ, Dept Internal Med, Nanjing, Jiangsu, Peoples R China
[6] Univ Nebraska Med Ctr, Dept Hematol & Oncol, Omaha, NE 68198 USA
关键词
failure; acute liver; fulminating hepatic failure; Hodgkin's disease; Hodgkin's lymphoma;
D O I
10.3402/jchimp.v4.25821
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Fulminant hepatic failure (FHF) is a relatively rare manifestation of Hodgkin's lymphoma. Clinical features, laboratory findings, and imaging of the liver are usually inconclusive, and liver biopsy may be required for confirmation. We present a case of an FHF in a woman 1 week after the diagnosis of Hodgkin's lymphoma. Chemotherapy could not be instituted due to hepatic encephalopathy and other complications. Autopsy revealed diffuse infiltration of the liver parenchyma. This case illustrates the importance of early diagnosis and institution of chemotherapy, which may reverse the liver failure.
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页数:4
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